Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 3/20 | 0.36 |
| ▸ | PRKCE | Q02156 | 2/20 | 0.32 |
| ▸ | MYLK | Q15746 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | PRKCG | P05129 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | PRKCA | P17252 | 1/20 | 0.32 |
| ▸ | APEX1 | P27695 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA4 | P22748 | 1/20 | 0.31 |
| ▸ | CA6 | P23280 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9313225 | 0.85 | MEN1 (0.31) | PTPN1PRKCEMYLKMEN1ALDH1A1 | |
| SCHEMBL9312627 | 0.82 | MEN1 (0.38) | MEN1ALDH1A1MAPTAPEX1RECQL | |
| SCHEMBL9312668 | 0.81 | ESR1 (0.33) | ALDH1A1 | |
| SCHEMBL9313613 | 0.78 | SELP (0.35) | ALDH1A1MAPTAPEX1RECQLTDP1 | |
| SCHEMBL9313582 | 0.74 | IAPP (0.39) | ALDH1A1RECQLTDP1CA1CA2 | |
| SCHEMBL9314760 | 0.73 | — | — | |
| SCHEMBL9313520 | 0.68 | HSP90AB1 (0.42) | — | |
| SCHEMBL9312656 | 0.68 | MAPT (0.48) | MEN1ALDH1A1MAPTAPEX1RECQL | |
| SCHEMBL30940420 | 0.64 | AKR1B1 (0.52) | PTPN1PRKCEMEN1ALDH1A1MAPT | |
| SCHEMBL9313082 | 0.63 | MEN1 (0.37) | PTPN1PRKCEMYLKMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5366996-A | Administering hydroxamic acids | ELFORD HOWARD L (US) | 1994-11-22 | — | — | US | disclosed |
| US-5183828-A | Ribonucleotide reductase inhibitor and free radical scavenger | RIET BARTHOLOMEUS VAN T (US) | 1993-02-02 | — | — | US | disclosed |
| US-4942253-A | INHIBITORS OF RIBONUCLEOTIDE REDUCTASE, ANTITUMOR AGENTS, LEUKEMIA, FREE RADICAL SCAVENGERS | RIET BARTHOLOMEUS VAN T (US) | 1990-07-17 | — | — | US | disclosed |
| US-4623659-A | RIBONUCLEOTIDE REDUCTASE INHIBITORS | RIET BARTHOLOMEUS VAN T (US) | 1986-11-18 | — | — | US | disclosed |