Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SELP | P16109 | 5/20 | 0.35 |
| ▸ | SELE | P16581 | 4/20 | 0.35 |
| ▸ | SELL | P14151 | 4/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | NSD2 | O96028 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | ALPL | P05186 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | ALPI | P09923 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | ALPG | P10696 | 1/20 | 0.31 |
| ▸ | APEX1 | P27695 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | CASP6 | P55212 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9313520 | 0.82 | HSP90AB1 (0.42) | — | |
| SCHEMBL9312656 | 0.81 | MAPT (0.48) | KDM4EALDH1A1LMNAPOLBGAA | |
| SCHEMBL9312639 | 0.78 | PTPN1 (0.36) | ALDH1A1MAPTAPEX1RECQLTDP1 | |
| SCHEMBL9313225 | 0.76 | MEN1 (0.31) | ALDH1A1POLBMAPTAPEX1RECQL | |
| SCHEMBL9312627 | 0.72 | MEN1 (0.38) | KDM4EALDH1A1LMNAPOLBGAA | |
| SCHEMBL9313926 | 0.71 | CYP2D6 (0.35) | SELPSELESELLKDM4ENSD2 | |
| SCHEMBL11052430 | 0.71 | HDAC6 (0.52) | SELPSELESELLKDM4ENSD2 | |
| SCHEMBL9312668 | 0.71 | ESR1 (0.33) | KDM4EALDH1A1 | |
| SCHEMBL9314760 | 0.70 | — | — | |
| SCHEMBL9313582 | 0.68 | IAPP (0.39) | KDM4EALDH1A1LMNARECQLTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5366996-A | Administering hydroxamic acids | ELFORD HOWARD L (US) | 1994-11-22 | — | — | US | disclosed |
| US-5183828-A | Ribonucleotide reductase inhibitor and free radical scavenger | RIET BARTHOLOMEUS VAN T (US) | 1993-02-02 | — | — | US | disclosed |
| EP-0144396-B1 | POLYHYDROXYBENZOIC ACID DERIVATIVES | VAN'T RIET, Bartholomeus (US) | 1991-01-02 | — | — | EP | disclosed |
| US-4942253-A | INHIBITORS OF RIBONUCLEOTIDE REDUCTASE, ANTITUMOR AGENTS, LEUKEMIA, FREE RADICAL SCAVENGERS | RIET BARTHOLOMEUS VAN T (US) | 1990-07-17 | — | — | US | disclosed |
| US-4623659-A | RIBONUCLEOTIDE REDUCTASE INHIBITORS | RIET BARTHOLOMEUS VAN T (US) | 1986-11-18 | — | — | US | disclosed |
| EP-0144396-A4 | POLYHYDROXYBENZOIC ACID DERIVATIVES. | RIET BARTHOLOMEUS VAN T (US) | 1986-08-21 | — | — | EP | disclosed |
| EP-0144396-A1 | POLYHYDROXYBENZOIC ACID DERIVATIVES. | RIET BARTHOLOMEUS VAN T (US) | 1985-06-19 | — | — | EP | disclosed |
| WO-1984004676-A1 | POLYHYDROXYBENZOIC ACID DERIVATIVES | RIET BARTHOLOMEUS VAN T | 1984-12-06 | — | — | WO | disclosed |