SCHEMBL9312643

SCHEMBL9312643

C=C/C=C(\c1ccc(OC)cc1)c1ccc(N(C)C)cc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 1/20 0.51
MAPT P10636 7/20 0.50
NPC1 O15118 2/20 0.50
RAB9A P51151 2/20 0.50
SMN1; SMN2 Q16637 2/20 0.50
GAA P10253 1/20 0.50
SLC2A1 P11166 1/20 0.49
CYP1A2 P05177 3/20 0.48
MEN1 O00255 3/20 0.48
KMT2A Q03164 3/20 0.48
TSHR P16473 2/20 0.48
CYP3A4 P08684 2/20 0.48
CYP2C19 P33261 2/20 0.48
LMNA P02545 1/20 0.48
TP53 P04637 1/20 0.46
ESR2 Q92731 1/20 0.46
NOX1 Q9Y5S8 1/20 0.46
ALDH1A1 P00352 3/20 0.46
HPGD P15428 3/20 0.46
KDM4E B2RXH2 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10683405 1.00 MAOB (0.51) MAOBMAPTNPC1RAB9ASMN1; SMN2
SCHEMBL9312644 1.00 MAOB (0.51) MAOBMAPTNPC1RAB9ASMN1; SMN2
SCHEMBL10685379 0.88 ALDH1A1 (0.57) MAPTSMN1; SMN2TSHRCYP3A4CYP2C19
SCHEMBL9313917 0.88 ALDH1A1 (0.48) MAPTNPC1RAB9ASMN1; SMN2GAA
SCHEMBL10686974 0.84 MEN1 (0.53) MAOBMAPTNPC1RAB9ASMN1; SMN2
SCHEMBL10686970 0.84 MEN1 (0.53) MAOBMAPTNPC1RAB9ASMN1; SMN2
SCHEMBL5070722 0.84 MAOB (0.55) MAOBMAPTNPC1RAB9ASMN1; SMN2
SCHEMBL5070723 0.84 MAOB (0.55) MAOBMAPTNPC1RAB9ASMN1; SMN2
SCHEMBL9312591 0.83 MAOB (0.54) MAOBMAPTNPC1RAB9ASMN1; SMN2
SCHEMBL10681501 0.83 MAOB (0.54) MAOBMAPTNPC1RAB9ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5286702-A Color coupler for infrared recording YAMADA CHEMICAL CO., LTD. (JP) 1994-02-15 US disclosed