Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.74 |
| ▸ | GAA | P10253 | 2/20 | 0.74 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.64 |
| ▸ | MEN1 | O00255 | 2/20 | 0.64 |
| ▸ | USP2 | O75604 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | POLB | P06746 | 2/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.59 |
| ▸ | CASP6 | P55212 | 1/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9312776 | 0.94 | GAA (0.84) | TSHRGAACYP2C19KMT2AMEN1 | |
| SCHEMBL2007035 | 0.90 | MEN1 (0.76) | TSHRKMT2AMEN1USP2ALDH1A1 | |
| SCHEMBL8752422 | 0.86 | GAA (0.77) | TSHRGAACYP2C19KMT2AMEN1 | |
| SCHEMBL30634403 | 0.86 | GAA (0.77) | TSHRGAACYP2C19KMT2AMEN1 | |
| SCHEMBL5188518 | 0.85 | GAA (0.81) | TSHRGAACYP2C19KMT2AMEN1 | |
| SCHEMBL2605742 | 0.84 | MEN1 (0.64) | TSHRKMT2AMEN1USP2ALDH1A1 | |
| SCHEMBL14817489 | 0.84 | KMT2A (0.68) | TSHRKMT2AMEN1USP2ALDH1A1 | |
| SCHEMBL4780753 | 0.83 | SMN1; SMN2 (0.72) | TSHRGAAKMT2AMEN1USP2 | |
| SCHEMBL19026947 | 0.83 | ALDH1A1 (0.67) | TSHRKMT2AMEN1USP2ALDH1A1 | |
| SCHEMBL18101767 | 0.83 | GAA (0.77) | TSHRGAACYP2C19KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5338642-A | Diazo type recording material comprising two couplers wherein the novel coupler used is a bis-malonamide | FUJI PHOTO FILM CO., LTD. (JP) | 1994-08-16 | — | — | US | disclosed |