Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | PARP1 | P09874 | 1/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | PDE8B | O95263 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10323879 | 0.91 | ATM (0.38) | ATMALDH1A1PARP1OPRK1MEN1 | |
| SCHEMBL10323472 | 0.87 | ATM (0.36) | ATMALDH1A1PARP1OPRK1PDE8B | |
| SCHEMBL9313102 | 0.85 | GPR119 (0.37) | ATMALDH1A1OPRK1HSD17B10RECQL | |
| SCHEMBL9313113 | 0.85 | GPR119 (0.37) | ATMALDH1A1OPRK1HSD17B10RECQL | |
| SCHEMBL9313107 | 0.85 | GPR119 (0.37) | ATMALDH1A1OPRK1HSD17B10RECQL | |
| SCHEMBL10325159 | 0.81 | HSD17B10 (0.37) | ALDH1A1MEN1KMT2AL3MBTL1HSD17B10 | |
| SCHEMBL13577617 | 0.81 | NR1H2 (0.38) | ATMALDH1A1OPRK1MEN1KMT2A | |
| SCHEMBL19942887 | 0.81 | NR1H2 (0.38) | ATMALDH1A1OPRK1MEN1KMT2A | |
| SCHEMBL376323 | 0.81 | NR1H2 (0.38) | ATMALDH1A1OPRK1MEN1KMT2A | |
| SCHEMBL15273386 | 0.81 | NR1H2 (0.38) | ATMALDH1A1OPRK1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5322852-A | Antitumor, antiprotozoa agents | CIBA-GEIGY CORP. (US) | 1994-06-21 | — | — | US | disclosed |
| EP-0558443-A1 | O-Piperidyl-(3/4)-hydroxylamines and O-piperidyl-(3/4)-alkyl-hydroxylamines and their use as ornithine decarboxylase inhibitors | CIBA-GEIGY AG (CH) | 1993-09-01 | — | — | EP | disclosed |