Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 1/20 | 0.41 |
| ▸ | KDM1A | O60341 | 8/20 | 0.40 |
| ▸ | SLC9A1 | P19634 | 4/20 | 0.37 |
| ▸ | MAOB | P27338 | 3/20 | 0.36 |
| ▸ | KMO | O15229 | 2/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.34 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | BACE1 | P56817 | 2/20 | 0.34 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.33 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.33 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.33 |
| ▸ | CHRNB3 | Q05901 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9313123 | 1.00 | GRM2 (0.41) | GRM2KDM1ASLC9A1MAOBKMO | |
| SCHEMBL9313128 | 1.00 | GRM2 (0.41) | GRM2KDM1ASLC9A1MAOBKMO | |
| SCHEMBL9313132 | 1.00 | GRM2 (0.41) | GRM2KDM1ASLC9A1MAOBKMO | |
| SCHEMBL9313264 | 0.91 | KDM1A (0.38) | GRM2KDM1AMAOBKMOS1PR3 | |
| SCHEMBL8381567 | 0.91 | KDM1A (0.38) | GRM2KDM1AMAOBKMOS1PR3 | |
| SCHEMBL8381570 | 0.91 | KDM1A (0.38) | GRM2KDM1AMAOBKMOS1PR3 | |
| SCHEMBL9313268 | 0.91 | KDM1A (0.38) | GRM2KDM1AMAOBKMOS1PR3 | |
| SCHEMBL8380295 | 0.90 | S1PR3 (0.38) | KDM1AMAOBKMOS1PR1S1PR3 | |
| SCHEMBL8518088 | 0.90 | KDM1A (0.42) | GRM2KDM1AMAOB | |
| SCHEMBL8380292 | 0.90 | S1PR3 (0.38) | KDM1AMAOBKMOS1PR1S1PR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5292452-A | Electrooptical devices; high dielectric anisotropy, low rotation viscosity, short response time | HOFFMANN-LA ROCHE INC. (US) | 1994-03-08 | — | — | US | disclosed |