Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ELANE | P08246 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | SRC | P12931 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 6/20 | 0.36 |
| ▸ | MAOB | P27338 | 6/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | UNG | P13051 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7992906 | 0.91 | POLB (0.50) | POLBALDH1A1NPC1KMT2ARAB9A | |
| SCHEMBL9313716 | 0.84 | ELANE (0.53) | ALDH1A1NPC1KMT2ARAB9AMAPT | |
| SCHEMBL10990952 | 0.80 | NPC1 (0.50) | POLBALDH1A1NPC1KMT2ARAB9A | |
| SCHEMBL16959815 | 0.79 | ELANE (0.49) | POLBALDH1A1NPC1KMT2ARAB9A | |
| SCHEMBL2472047 | 0.78 | ELANE (0.47) | POLBALDH1A1NPC1KMT2ARAB9A | |
| SCHEMBL8458900 | 0.77 | NPC1 (0.55) | POLBALDH1A1NPC1KMT2ARAB9A | |
| SCHEMBL8579838 | 0.77 | SRC (0.58) | POLBALDH1A1NPC1KMT2ARAB9A | |
| SCHEMBL11567850 | 0.76 | POLB (0.50) | POLBALDH1A1NPC1KMT2ARAB9A | |
| SCHEMBL3066413 | 0.76 | SRC (0.44) | POLBALDH1A1NPC1KMT2ARAB9A | |
| SCHEMBL13845254 | 0.75 | ELANE (0.51) | POLBALDH1A1NPC1KMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5356752-A | Compounds with acid-labile protective groups useful in positive-working radiation-sensitive mixtures | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-10-18 | — | — | US | disclosed |