Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | JAK2 | O60674 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | CYP11B1 | P15538 | 4/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 4/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.31 |
| ▸ | HTR7 | P34969 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | ACACB | O00763 | 2/20 | 0.30 |
| ▸ | ACACA | Q13085 | 2/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | APP | P05067 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9313856 | 1.00 | FFAR1 (0.33) | FFAR1JAK2HDAC2CYP11B1CYP11B2 | |
| SCHEMBL8380314 | 1.00 | FFAR1 (0.33) | FFAR1JAK2HDAC2CYP11B1CYP11B2 | |
| SCHEMBL8380316 | 1.00 | FFAR1 (0.33) | FFAR1JAK2HDAC2CYP11B1CYP11B2 | |
| SCHEMBL8380307 | 0.89 | HTR2A (0.37) | SLC6A2SLC6A4SLC6A3PTGS2DGAT1 | |
| SCHEMBL9311766 | 0.89 | HTR2A (0.37) | SLC6A2SLC6A4SLC6A3PTGS2DGAT1 | |
| SCHEMBL9311770 | 0.89 | HTR2A (0.37) | SLC6A2SLC6A4SLC6A3PTGS2DGAT1 | |
| SCHEMBL8380305 | 0.89 | HTR2A (0.37) | SLC6A2SLC6A4SLC6A3PTGS2DGAT1 | |
| SCHEMBL8962836 | 0.88 | JAK2 (0.35) | FFAR1JAK2HDAC2CYP11B1CYP11B2 | |
| SCHEMBL8962842 | 0.88 | JAK2 (0.35) | FFAR1JAK2HDAC2CYP11B1CYP11B2 | |
| SCHEMBL9311930 | 0.87 | AHR (0.41) | HDAC2SLC6A2SLC6A4SLC6A3DGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5292452-A | Electrooptical devices; high dielectric anisotropy, low rotation viscosity, short response time | HOFFMANN-LA ROCHE INC. (US) | 1994-03-08 | — | — | US | disclosed |