Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGF1 | P05230 | 4/20 | 0.50 |
| ▸ | FGF2 | P09038 | 2/20 | 0.50 |
| ▸ | F10 | P00742 | 3/20 | 0.38 |
| ▸ | SERPINC1 | P01008 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | HPSE | Q9Y251 | 7/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9315067 | 1.00 | FGF1 (0.50) | FGF1FGF2F10SERPINC1CA2 | |
| SCHEMBL3432864 | 0.87 | FGF1 (0.46) | FGF1FGF2F10CA2 | |
| SCHEMBL9106001 | 0.85 | FGF1 (0.42) | FGF1FGF2F10SERPINC1CA2 | |
| SCHEMBL8781293 | 0.85 | FGF1 (0.42) | FGF1FGF2F10SERPINC1CA2 | |
| SCHEMBL4957225 | 0.84 | CXCL10 (0.43) | FGF1FGF2F10CA2 | |
| SCHEMBL2466010 | 0.84 | CXCL10 (0.43) | FGF1FGF2F10CA2 | |
| SCHEMBL8331004 | 0.83 | FGF1 (0.40) | FGF1FGF2F10SERPINC1CA2 | |
| SCHEMBL8781311 | 0.82 | FGF1 (0.42) | FGF1FGF2F10SERPINC1CA2 | |
| SCHEMBL5178539 | 0.82 | FGF1 (0.42) | FGF1FGF2F10SERPINC1CA2 | |
| SCHEMBL2524663 | 0.82 | FGF1 (0.62) | FGF1FGF2F10SERPINC1HPSE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5358936-A | Antiinflammatory agents | Gordon, Paul (US) | 1994-10-25 | — | — | US | disclosed |
| US-5095104-A | Antiinflammatory, anitulcer | GORDON PAUL (US) | 1992-03-10 | — | — | US | disclosed |