Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 8/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | BLM | P54132 | 6/20 | 0.43 |
| ▸ | TSHR | P16473 | 4/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 6/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.42 |
| ▸ | RECQL | P46063 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | ADRB2 | P07550 | 3/20 | 0.42 |
| ▸ | APEX1 | P27695 | 3/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9314014 | 1.00 | APP (0.49) | APPKDM4ETDP1MAPK1POLB | |
| SCHEMBL186927 | 0.91 | APP (0.51) | APPKDM4ETDP1MAPK1BLM | |
| SCHEMBL186928 | 0.91 | APP (0.51) | APPKDM4ETDP1MAPK1BLM | |
| SCHEMBL3838056 | 0.88 | TRPA1 (0.46) | APPKDM4ETDP1MAPK1POLB | |
| SCHEMBL5283420 | 0.87 | CA12 (0.53) | KDM4ETDP1MAPK1POLBBLM | |
| SCHEMBL5283426 | 0.87 | CA12 (0.53) | KDM4ETDP1MAPK1POLBBLM | |
| SCHEMBL12659990 | 0.85 | TSHR (0.49) | APPKDM4EPOLBBLMTSHR | |
| SCHEMBL11860283 | 0.85 | TSHR (0.64) | KDM4EPOLBBLMTSHRNPSR1 | |
| SCHEMBL11860271 | 0.85 | TSHR (0.64) | KDM4EPOLBBLMTSHRNPSR1 | |
| SCHEMBL5281995 | 0.80 | BLM (0.51) | KDM4ETDP1MAPK1POLBBLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5366996-A | Administering hydroxamic acids | ELFORD HOWARD L (US) | 1994-11-22 | — | — | US | disclosed |