Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTPA | P49638 | 2/20 | 0.59 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | PDE4A | P27815 | 1/20 | 0.43 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 4/20 | 0.42 |
| ▸ | BCHE | P06276 | 3/20 | 0.42 |
| ▸ | PSEN1 | P49768 | 4/20 | 0.42 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9255784 | 0.91 | TTPA (0.51) | TTPAALOX5MEN1KMT2APDE4A | |
| SCHEMBL9312837 | 0.87 | PTGS1 (0.55) | ACHEBCHEPTGS1PTGS2CYP1A2 | |
| SCHEMBL9312754 | 0.83 | TTPA (0.60) | TTPAALOX5MEN1KMT2APDE4A | |
| SCHEMBL9312772 | 0.79 | TTPA (0.76) | TTPAALOX5MEN1KMT2APDE4A | |
| SCHEMBL9252607 | 0.78 | TTPA (0.57) | TTPAALOX5MEN1KMT2APDE4A | |
| SCHEMBL9313720 | 0.77 | TTPA (0.58) | TTPAALOX5MEN1KMT2APDE4A | |
| SCHEMBL9656538 | 0.77 | TTPA (0.64) | TTPAALOX5MEN1KMT2APDE4A | |
| SCHEMBL9250008 | 0.77 | TTPA (0.56) | TTPAALOX5MEN1KMT2APDE4A | |
| SCHEMBL2059270 | 0.77 | TTPA (0.67) | TTPAALOX5MEN1KMT2APDE4A | |
| SCHEMBL9257093 | 0.76 | PTGS1 (0.48) | ACHEBCHEPTGS1PTGS2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5315017-A | Peroxidation and eicosanoid biosynthesis inhibition | ADIR ET COMPAGNIE (FR) | 1994-05-24 | — | — | US | disclosed |
| EP-0512899-A1 | Benzopyran compounds, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1992-11-11 | — | — | EP | disclosed |