Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP8 | Q6V1X1 | 3/20 | 0.41 |
| ▸ | DPP7 | Q9UHL4 | 3/20 | 0.41 |
| ▸ | ANPEP | P15144 | 1/20 | 0.39 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.39 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.39 |
| ▸ | DPP4 | P27487 | 2/20 | 0.38 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | NPY4R | P50391 | 5/20 | 0.37 |
| ▸ | NPY1R | P25929 | 3/20 | 0.36 |
| ▸ | NPY2R | P49146 | 2/20 | 0.36 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.36 |
| ▸ | CCR6 | P51684 | 1/20 | 0.36 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.36 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.35 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.35 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9128839 | 0.95 | LTA4H (0.40) | DPP8DPP7ANPEPSLC1A3SLC1A1 | |
| SCHEMBL7353231 | 0.92 | HTT (0.41) | DPP8DPP7ANPEPSLC1A3SLC1A1 | |
| SCHEMBL7358353 | 0.91 | DPP8 (0.40) | DPP8DPP7ANPEPSLC1A3SLC1A1 | |
| SCHEMBL27892485 | 0.84 | NPY4R (0.42) | DPP8DPP7ANPEPSLC1A3SLC1A1 | |
| SCHEMBL29517152 | 0.82 | FOLH1 (0.42) | DPP8DPP7ANPEPSLC1A3SLC1A1 | |
| SCHEMBL29766659 | 0.81 | DPP8 (0.43) | DPP8DPP7ANPEPSLC1A3SLC1A1 | |
| SCHEMBL11009035 | 0.80 | HTR2C (0.39) | DPP8DPP7DPP4DPP9HTT | |
| SCHEMBL3362561 | 0.80 | DPP8 (0.50) | DPP8DPP7ANPEPSLC1A3SLC1A1 | |
| SCHEMBL22133069 | 0.80 | DPP8 (0.50) | DPP8DPP7ANPEPSLC1A3SLC1A1 | |
| SCHEMBL7758995 | 0.80 | DPP8 (0.50) | DPP8DPP7ANPEPSLC1A3SLC1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5292652-A | For cleaving Met-Asp bond | ATHENA NEUROSCIENCES, INC. (US) | 1994-03-08 | — | — | US | disclosed |
| WO-1992007068-A1 | AMYLOIDIN PROTEASE AND USES THEREOF | ATHENA NEUROSCIENCES, INC. (US) | 1992-04-30 | — | — | WO | disclosed |