Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 1/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.41 |
| ▸ | TRPV4 | Q9HBA0 | 3/20 | 0.41 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.39 |
| ▸ | FEN1 | P39748 | 1/20 | 0.39 |
| ▸ | AR | P10275 | 8/20 | 0.37 |
| ▸ | KIF11 | P52732 | 3/20 | 0.35 |
| ▸ | CES2 | O00748 | 1/20 | 0.34 |
| ▸ | PDE2A | O00408 | 2/20 | 0.34 |
| ▸ | PGR | P06401 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19903462 | 0.85 | CYP11B1 (0.48) | CYP11B1CYP11B2TRPV4ALOX5APFEN1 | |
| SCHEMBL463526 | 0.80 | ALOX5AP (0.40) | CYP11B1CYP11B2TRPV4ALOX5APFEN1 | |
| SCHEMBL27614015 | 0.80 | CYP11B1 (0.40) | CYP11B1CYP11B2TRPV4ALOX5APFEN1 | |
| SCHEMBL18245321 | 0.80 | CYP11B1 (0.40) | CYP11B1CYP11B2TRPV4ALOX5APFEN1 | |
| SCHEMBL9465161 | 0.80 | AR (0.42) | CYP11B1CYP11B2TRPV4AR | |
| SCHEMBL31435045 | 0.80 | CYP11B1 (0.36) | CYP11B1CYP11B2TRPV4ALOX5APFEN1 | |
| SCHEMBL31195171 | 0.80 | AR (0.42) | CYP11B1CYP11B2TRPV4AR | |
| SCHEMBL9465482 | 0.80 | CYP11B1 (0.36) | CYP11B1CYP11B2TRPV4ALOX5APFEN1 | |
| SCHEMBL22822434 | 0.79 | RXRA (0.47) | CYP11B1CYP11B2TRPV4ALOX5APFEN1 | |
| SCHEMBL24743943 | 0.79 | AR (0.38) | CYP11B1CYP11B2TRPV4AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5300676-A | Herbicidal fluorine-substituted alpha-(5-aryloxynaphthalen-1-yl-oxy)-propionic acid derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 1994-04-05 | — | — | US | disclosed |
| US-5196593-A | HALOGENATED TRIFLUOROMETHYLBENZENES | OCCIDENTAL CHEMICAL CORPORATION (US) | 1993-03-23 | — | — | US | disclosed |
| EP-0453842-A2 | Fluor subsituted derivatives of alpha-(5-aryloxy-naphthalen-1-yloxy)propionic acid | BAYER AG (DE) | 1991-10-30 | — | — | EP | disclosed |