Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WEE1 | P30291 | 7/20 | 0.39 |
| ▸ | CHEK1 | O14757 | 6/20 | 0.39 |
| ▸ | CDK4 | P11802 | 4/20 | 0.39 |
| ▸ | CCND1 | P24385 | 4/20 | 0.39 |
| ▸ | CAMK2B | Q13554 | 1/20 | 0.39 |
| ▸ | CAMK2G | Q13555 | 1/20 | 0.39 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.39 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 5/20 | 0.36 |
| ▸ | GLI1 | P08151 | 1/20 | 0.34 |
| ▸ | GLI2 | P10070 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | CCNE2 | O96020 | 2/20 | 0.33 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.33 |
| ▸ | CDK2 | P24941 | 2/20 | 0.33 |
| ▸ | PRKACA | P17612 | 1/20 | 0.32 |
| ▸ | PRKACG | P22612 | 1/20 | 0.32 |
| ▸ | PRKACB | P22694 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3947648 | 0.82 | WEE1 (0.43) | WEE1CHEK1CDK4CCND1CAMK2B | |
| SCHEMBL7902735 | 0.81 | GSK3B (0.35) | WEE1CHEK1CDK4CCND1CAMK2B | |
| SCHEMBL3946790 | 0.77 | PARP1 (0.37) | WEE1CHEK1CDK4CCND1CAMK2B | |
| SCHEMBL7598198 | 0.75 | PARP1 (0.41) | WEE1CHEK1CDK4CCND1CAMK2B | |
| SCHEMBL7598089 | 0.72 | PARP1 (0.50) | WEE1CHEK1PARP1MAOAMAOB | |
| SCHEMBL29541 | 0.72 | PARP1 (0.50) | WEE1CHEK1PARP1MAOAMAOB | |
| SCHEMBL30606639 | 0.72 | PARP1 (0.50) | WEE1CHEK1PARP1MAOAMAOB | |
| SCHEMBL7601076 | 0.72 | PARP1 (0.50) | WEE1CHEK1PARP1MAOAMAOB | |
| SCHEMBL16855803 | 0.71 | PARP1 (0.49) | CHEK1CDK4CCND1CAMK2BCAMK2G | |
| SCHEMBL2854316 | 0.71 | PARP1 (0.36) | WEE1CHEK1CDK4CCND1CAMK2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0591375-A1 | COMPOSITE ARTICLE COMPRISING ORIENTED MICROSTRUCTURES. | MINNESOTA MINING & MFG (US) | 1994-04-13 | — | — | EP | disclosed |
| WO-1993000560-A1 | COMPOSITE ARTICLE COMPRISING ORIENTED MICROSTRUCTURES | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1993-01-07 | — | — | WO | disclosed |