Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 7/20 | 0.41 |
| ▸ | CDK4 | P11802 | 3/20 | 0.40 |
| ▸ | CCND1 | P24385 | 3/20 | 0.40 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.40 |
| ▸ | CDK2 | P24941 | 1/20 | 0.40 |
| ▸ | GSK3B | P49841 | 1/20 | 0.40 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.40 |
| ▸ | PPOX | P50336 | 1/20 | 0.38 |
| ▸ | WEE1 | P30291 | 5/20 | 0.38 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | RGS12 | O14924 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | APEX1 | P27695 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20718128 | 0.80 | BCL2 (0.40) | PARP1CDK4CCND1CCNA2CDK2 | |
| SCHEMBL7601076 | 0.80 | PARP1 (0.50) | PARP1GSK3BPPOXWEE1CHEK1 | |
| SCHEMBL30606639 | 0.80 | PARP1 (0.50) | PARP1GSK3BPPOXWEE1CHEK1 | |
| SCHEMBL7598089 | 0.80 | PARP1 (0.50) | PARP1GSK3BPPOXWEE1CHEK1 | |
| SCHEMBL29541 | 0.80 | PARP1 (0.50) | PARP1GSK3BPPOXWEE1CHEK1 | |
| SCHEMBL3946790 | 0.79 | PARP1 (0.37) | PARP1CDK4CCND1CCNA2CDK2 | |
| SCHEMBL15088598 | 0.78 | GSK3B (0.49) | PARP1CDK4CCND1CCNA2CDK2 | |
| SCHEMBL17225997 | 0.76 | PARP1 (0.40) | PARP1CDK4CCND1CCNA2CDK2 | |
| SCHEMBL9314360 | 0.75 | WEE1 (0.39) | PARP1CDK4CCND1CDK2WEE1 | |
| SCHEMBL17795644 | 0.75 | PARP1 (0.49) | PARP1GSK3BMEN1RGS12USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1266222-A2 | VISUALLY DETECTABLE DYE LABELLED BIOMOLECULES FOR ANALYSIS | Genigma Corporation (US) | 2002-12-18 | — | — | EP | disclosed |
| WO-2001069254-A2 | VISUALLY DETECTABLE DYE LABELLED BIOMOLECULES FOR ANALYSIS | GENIGMA CORPORATION (US) | 2001-09-20 | — | — | WO | disclosed |