Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.59 |
| ▸ | HPGD | P15428 | 4/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.59 |
| ▸ | MEN1 | O00255 | 3/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.59 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.59 |
| ▸ | HNF4A | P41235 | 4/20 | 0.55 |
| ▸ | ACMSD | Q8TDX5 | 4/20 | 0.55 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.55 |
| ▸ | DHFR | P00374 | 1/20 | 0.55 |
| ▸ | CA1 | P00915 | 3/20 | 0.52 |
| ▸ | CA2 | P00918 | 3/20 | 0.52 |
| ▸ | CA12 | O43570 | 2/20 | 0.52 |
| ▸ | CA7 | P43166 | 2/20 | 0.52 |
| ▸ | CA9 | Q16790 | 2/20 | 0.52 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9654462 | 1.00 | ALDH1A1 (0.59) | ALDH1A1KDM4EHPGDTDP1KMT2A | |
| SCHEMBL11489364 | 0.98 | ALDH1A1 (0.57) | ALDH1A1KDM4EHPGDTDP1KMT2A | |
| SCHEMBL9755165 | 0.92 | KDM4E (0.67) | ALDH1A1KDM4EHPGDTDP1KMT2A | |
| SCHEMBL14124058 | 0.88 | CA1 (0.56) | ALDH1A1KDM4EHPGDTDP1KMT2A | |
| SCHEMBL11474260 | 0.86 | ALDH1A1 (0.50) | ALDH1A1KDM4EHPGDTDP1KMT2A | |
| SCHEMBL11481523 | 0.86 | KDM4E (0.56) | ALDH1A1KDM4EHPGDTDP1KMT2A | |
| SCHEMBL25017789 | 0.85 | KDM4E (0.59) | ALDH1A1KDM4EHPGDTDP1KMT2A | |
| SCHEMBL28488996 | 0.85 | HSD17B10 (0.56) | ALDH1A1KDM4EHPGDTDP1KMT2A | |
| Zinc Ion SCHEMBL11489362 | 0.84 | ALDH1A1 (0.47) | ALDH1A1KDM4EHPGDTDP1KMT2A | |
| SCHEMBL658651 | 0.82 | KDM4E (0.56) | ALDH1A1KDM4EHPGDTDP1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5354907-A | Salt formation of tris/p-hydroxyphenyl/ethane, oxyalkylation with ethylene oxide or propylene oxide, catalytic reductive amination | HOECHST CELANESE CORPORATION (US) | 1994-10-11 | — | — | US | disclosed |
| US-5312988-A | Tris/p-hydroxyphenyl/ethane | HOECHST CELANESE CORPORATION (US) | 1994-05-17 | — | — | US | disclosed |
| US-5300589-A | Chemical intermediates of tris/p-hydroxyalkyloxyphenyl/ethane or tris/p-hydroxyphenyl/ethane modified polyethers | HOECHST CELANESE CORPORATION (US) | 1994-04-05 | — | — | US | disclosed |
| US-5300559-A | Tris/p-hydroxyphenyl/benzene ether alkyleneoxy amine or modified polyethers; chemical intermediates | HOECHST CELANESE CORPORATION (US) | 1994-04-05 | — | — | US | disclosed |
| US-RE31467-E | ANTIINFLAMMATORY AGENTS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1983-12-20 | — | — | US | disclosed |
| US-4152341-A | ANTIINFLAMMATORY | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1979-05-01 | — | — | US | disclosed |
| US-4113879-A | TRIPHENYLMETHANEDICARBOXYLIC ACIDS, ANTI-INFLAMMATORY AGENTS | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1978-09-12 | — | — | US | disclosed |