Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 3/20 | 0.54 |
| ▸ | RARG | P13631 | 3/20 | 0.54 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.52 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.52 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.52 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.52 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.52 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.52 |
| ▸ | TNKS | O95271 | 1/20 | 0.48 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | CYP26A1 | O43174 | 3/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | RARA | P10276 | 2/20 | 0.40 |
| ▸ | PGR | P06401 | 1/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.40 |
| ▸ | BLVRB | P30043 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31714495 | 0.89 | HDAC3 (0.52) | RARBRARGHDAC3HDAC4HDAC1 | |
| SCHEMBL3150642 | 0.89 | HDAC3 (0.52) | RARBRARGHDAC3HDAC4HDAC1 | |
| SCHEMBL9313849 | 0.85 | HDAC3 (0.49) | RARBRARGHDAC3HDAC4HDAC1 | |
| SCHEMBL9314264 | 0.84 | MEN1 (0.53) | RARBRARGHDAC3HDAC4HDAC1 | |
| SCHEMBL9312256 | 0.82 | RARB (0.51) | RARBRARGHDAC3HDAC4HDAC1 | |
| SCHEMBL9313154 | 0.81 | TNKS (0.50) | RARBRARGHDAC3HDAC4HDAC1 | |
| SCHEMBL9866488 | 0.81 | TNKS (0.52) | RARBRARGHDAC3HDAC4HDAC1 | |
| SCHEMBL9313377 | 0.81 | MAPT (0.55) | HDAC3HDAC4HDAC1HDAC2HDAC8 | |
| SCHEMBL9313383 | 0.81 | MAPT (0.55) | HDAC3HDAC4HDAC1HDAC2HDAC8 | |
| SCHEMBL9865756 | 0.80 | MEN1 (0.55) | RARBRARGHDAC3HDAC4HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5373019-A | Pharmaceutical lactam compositions for inhibition of erythrocyte and thrombocyte aggregation | BOEHRINGER MANNHEIM GMBH (DE) | 1994-12-13 | — | — | US | disclosed |
| US-4985448-A | Ureidoindoles, pharmaceutical compositions and methods for erythrocyte and thrombocyte aggregation inhibition | BOEHRINGER MANNHEIM GMBH (DE) | 1991-01-15 | — | — | US | disclosed |