Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.54 |
| ▸ | EGFR | P00533 | 7/20 | 0.50 |
| ▸ | MMP1 | P03956 | 6/20 | 0.50 |
| ▸ | MMP2 | P08253 | 6/20 | 0.50 |
| ▸ | MMP9 | P14780 | 6/20 | 0.50 |
| ▸ | MAOB | P27338 | 3/20 | 0.50 |
| ▸ | MAOA | P21397 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.48 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9313377 | 1.00 | MAPT (0.55) | MAPTALDH1A1KDM4ETRPV1EGFR | |
| SCHEMBL9312463 | 0.90 | TRPV1 (0.56) | TRPV1MMP1MMP2MMP9MAOB | |
| SCHEMBL9312470 | 0.90 | TRPV1 (0.56) | TRPV1MMP1MMP2MMP9MAOB | |
| SCHEMBL9314210 | 0.89 | TRPV1 (0.53) | MAPTALDH1A1KDM4ETRPV1MEN1 | |
| SCHEMBL9312264 | 0.88 | NAMPT (0.49) | NPC1RAB9A | |
| SCHEMBL9313168 | 0.87 | MAPT (0.55) | MAPTALDH1A1KDM4ETRPV1EGFR | |
| SCHEMBL9313174 | 0.87 | MAPT (0.55) | MAPTALDH1A1KDM4ETRPV1EGFR | |
| SCHEMBL9312484 | 0.87 | ALDH1A1 (0.59) | MAPTALDH1A1TRPV1EGFRMMP1 | |
| SCHEMBL9312489 | 0.87 | ALDH1A1 (0.59) | MAPTALDH1A1TRPV1EGFRMMP1 | |
| SCHEMBL9312235 | 0.86 | TRPV1 (0.52) | MAPTALDH1A1KDM4ETRPV1MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5373019-A | Pharmaceutical lactam compositions for inhibition of erythrocyte and thrombocyte aggregation | BOEHRINGER MANNHEIM GMBH (DE) | 1994-12-13 | — | — | US | disclosed |
| US-4985448-A | Ureidoindoles, pharmaceutical compositions and methods for erythrocyte and thrombocyte aggregation inhibition | BOEHRINGER MANNHEIM GMBH (DE) | 1991-01-15 | — | — | US | disclosed |