Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OTC | P00480 | 1/20 | 0.35 |
| ▸ | NPY4R | P50391 | 7/20 | 0.35 |
| ▸ | NPY1R | P25929 | 5/20 | 0.35 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.34 |
| ▸ | NPY2R | P49146 | 4/20 | 0.33 |
| ▸ | NPY5R | Q15761 | 4/20 | 0.33 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | ITGB3 | P05106 | 4/20 | 0.32 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.32 |
| ▸ | NOS3 | P29474 | 1/20 | 0.31 |
| ▸ | NOS1 | P29475 | 1/20 | 0.31 |
| ▸ | NOS2 | P35228 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26104827 | 0.99 | OTC (0.36) | OTCNPY4RNPY1RDDAH1NPY2R | |
| Arginine SCHEMBL21592228 | 0.94 | OTC (0.43) | OTCNPY4RNPY1RDDAH1ALOX15 | |
| Arginine SCHEMBL21592230 | 0.94 | OTC (0.43) | OTCNPY4RNPY1RDDAH1ALOX15 | |
| SCHEMBL28712062 | 0.89 | NPY4R (0.39) | OTCNPY4RNPY1RDDAH1NPY2R | |
| SCHEMBL288133 | 0.89 | NPY4R (0.39) | OTCNPY4RNPY1RDDAH1NPY2R | |
| SCHEMBL9237239 | 0.89 | NPY4R (0.39) | OTCNPY4RNPY1RDDAH1NPY2R | |
| SCHEMBL2474862 | 0.88 | NPY4R (0.36) | OTCNPY4RNPY1RDDAH1NPY2R | |
| Hydrochloric Acid SCHEMBL8039440 | 0.88 | NPY4R (0.38) | OTCNPY4RNPY1RDDAH1NPY2R | |
| Hydrochloric Acid SCHEMBL8040222 | 0.88 | NPY4R (0.38) | OTCNPY4RNPY1RDDAH1NPY2R | |
| Malic Acid SCHEMBL11164058 | 0.88 | SMN1; SMN2 (0.40) | OTCNPY4RNPY1RDDAH1NPY2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5298621-A | Peptides endcapped with purine derivative | SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. (IT) | 1994-03-29 | — | — | US | disclosed |