SCHEMBL9314487

SCHEMBL9314487

C=CC(=C(c1ccc(N(C)C)cc1)c1ccc(N(C)C)cc1)C1(c2ccc(OC)c(OC)c2)OC(=O)c2cc(N(C)C)ccc21

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 2/20 0.46
HSD17B10 Q99714 2/20 0.46
ALDH1A1 P00352 1/20 0.46
HPGD P15428 1/20 0.46
HIF1A Q16665 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
MEN1 O00255 2/20 0.39
KMT2A Q03164 2/20 0.39
ABCB1 P08183 2/20 0.35
MAOA P21397 1/20 0.35
MAOB P27338 1/20 0.35
NQO2 P16083 1/20 0.34
MAPK14 Q16539 3/20 0.34
LMNA P02545 2/20 0.33
MAPT P10636 2/20 0.33
HTT P42858 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
KRAS P01116 1/20 0.32
TSHR P16473 2/20 0.32
GAA P10253 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9313241 0.89 CYP3A4 (0.47) CYP3A4HSD17B10ALDH1A1HPGDHIF1A
SCHEMBL9312454 0.89 CYP3A4 (0.47) CYP3A4HSD17B10ALDH1A1HPGDHIF1A
SCHEMBL9314735 0.85 ALDH1A1 (0.49) CYP3A4HSD17B10ALDH1A1HPGDHIF1A
SCHEMBL9313469 0.85 MEN1 (0.42) CYP3A4HSD17B10ALDH1A1HPGDHIF1A
SCHEMBL9312528 0.85 ALDH1A1 (0.49) CYP3A4HSD17B10ALDH1A1HPGDHIF1A
SCHEMBL9313090 0.83 ALDH1A1 (0.42) CYP3A4HSD17B10ALDH1A1HPGDHIF1A
SCHEMBL9313965 0.83 ALDH1A1 (0.45) CYP3A4HSD17B10ALDH1A1HPGDHIF1A
SCHEMBL9313962 0.82 ALDH1A1 (0.41) CYP3A4HSD17B10ALDH1A1HPGDHIF1A
SCHEMBL9313095 0.81 ALDH1A1 (0.46) CYP3A4HSD17B10ALDH1A1HPGDHIF1A
SCHEMBL9313534 0.80 ALDH1A1 (0.39) CYP3A4HSD17B10ALDH1A1HPGDHIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5286702-A Color coupler for infrared recording YAMADA CHEMICAL CO., LTD. (JP) 1994-02-15 US disclosed