SCHEMBL9314645

SCHEMBL9314645

C=Cc1cccc(COCCC[Si](C)(OC)OC)c1

nearest known ligand 0.35

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.35
TP53 P04637 1/20 0.35
NAAA Q02083 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31
TEAD3 Q99594 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9315828 0.90 TDP1 (0.35) TDP1TP53NAAAL3MBTL1MEN1
SCHEMBL9315480 0.88 TDP1 (0.36) TDP1TP53NAAAL3MBTL1MEN1
SCHEMBL9315466 0.85 TDP1 (0.36) TDP1TP53NAAAL3MBTL1TEAD3
SCHEMBL9314799 0.85 TDP1 (0.36) TDP1TP53NAAAL3MBTL1TEAD3
SCHEMBL8758524 0.85 TDP1 (0.33) TDP1TP53NAAAL3MBTL1MEN1
SCHEMBL8759059 0.83 TDP1 (0.35) TDP1L3MBTL1TEAD3
SCHEMBL9315789 0.82 TP53 (0.34) TDP1TP53NAAATEAD3
SCHEMBL9315946 0.82 TP53 (0.33) TDP1TP53NAAA
SCHEMBL10071521 0.82 TDP1 (0.40) TDP1TP53NAAAL3MBTL1MEN1
SCHEMBL10071516 0.82 TDP1 (0.40) TDP1TP53NAAAL3MBTL1TEAD3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5342983-A Polymer reforming agents SHIN-ETSU CHEMICAL CO., LTD. (JP) 1994-08-30 US disclosed