Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | NAAA | Q02083 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 2/20 | 0.32 |
| ▸ | AGXT | P21549 | 2/20 | 0.32 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.32 |
| ▸ | TEAD3 | Q99594 | 1/20 | 0.31 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9315828 | 0.88 | TDP1 (0.35) | TDP1TP53L3MBTL1MEN1KMT2A | |
| SCHEMBL9314645 | 0.88 | TDP1 (0.35) | TDP1TP53L3MBTL1MEN1KMT2A | |
| SCHEMBL9314685 | 0.87 | TP53 (0.34) | TDP1TP53NAAATEAD3 | |
| SCHEMBL8758524 | 0.86 | TDP1 (0.33) | TDP1TP53L3MBTL1MEN1KMT2A | |
| SCHEMBL9315466 | 0.84 | TDP1 (0.36) | TDP1TP53L3MBTL1NAAATEAD3 | |
| SCHEMBL9314799 | 0.84 | TDP1 (0.36) | TDP1TP53L3MBTL1NAAATEAD3 | |
| SCHEMBL9315789 | 0.83 | TP53 (0.34) | TDP1TP53NAAATEAD3 | |
| SCHEMBL8759752 | 0.83 | TDP1 (0.38) | TDP1TP53L3MBTL1MEN1KMT2A | |
| SCHEMBL10071521 | 0.83 | TDP1 (0.40) | TDP1TP53L3MBTL1MEN1KMT2A | |
| SCHEMBL11706078 | 0.83 | TP53 (0.40) | TDP1TP53TRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5342983-A | Polymer reforming agents | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1994-08-30 | — | — | US | disclosed |