Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL363382 | 0.66 | CYP2C19 (0.52) | CYP2C19HSD17B10 | |
| SCHEMBL3675948 | 0.65 | — | — | |
| SCHEMBL10605855 | 0.63 | CYP2C19 (0.44) | CYP2C19HSD17B10 | |
| SCHEMBL9314843 | 0.62 | TP53 (0.31) | TP53MAPTALOX15HSD17B10 | |
| SCHEMBL3031697 | 0.60 | ALDH1A1 (0.37) | CYP2C19HSD17B10 | |
| SCHEMBL11152672 | 0.57 | — | — | |
| SCHEMBL10491543 | 0.56 | — | — | |
| SCHEMBL1100011 | 0.56 | — | — | |
| SCHEMBL28421174 | 0.56 | ALDH1A1 (0.32) | HSD17B10 | |
| SCHEMBL10605562 | 0.55 | CYP2C19 (0.36) | CYP2C19MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5302752-A | Acetic acid derivatives and their production | ETHYL CORPORATION (US) | 1994-04-12 | — | — | US | disclosed |
| EP-0426333-A2 | Acetic acid derivatives and their production | ETHYL CORPORATION (US) | 1991-05-08 | — | — | EP | disclosed |
| EP-0336371-A2 | Gem-disubstituted cyclohexadienones and their production | ETHYL CORPORATION (US) | 1989-10-11 | — | — | EP | disclosed |
| US-4871877-A | Gem-disubstituted cyclohexadienones and their production | ETHYL CORPORATION (US) | 1989-10-03 | — | — | US | disclosed |
| US-4845258-A | Production of gem-disubstituted cyclohexadienones | ETHYL CORPORATION (US) | 1989-07-04 | — | — | US | disclosed |
| US-4804774-A | Production of gem-disubstituted cyclohexadienones | ETHYL CORPORATION (US) | 1989-02-14 | — | — | US | disclosed |
| US-4804772-A | Gem-disubstituted cyclohexadienones and their production | ETHYL CORPORATION (US) | 1989-02-14 | — | — | US | disclosed |
| US-4804773-A | Production of gem-disubstituted cyclohexadienones | ETHYL CORPORATION (US) | 1989-02-14 | — | — | US | disclosed |
| US-4634787-A | Process for preparing (2,2,2-trihalo-1, 1-dihydrocarbyl-ethoxy) trihydrocarbylsilanes | THE DOW CHEMICAL COMPANY (US) | 1987-01-06 | — | — | US | disclosed |