Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFTR | P13569 | 1/20 | 0.42 |
| ▸ | BAZ2B | Q9UIF8 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | STAT3 | P40763 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | FASN | P49327 | 11/20 | 0.40 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.39 |
| ▸ | MAPK7 | Q13164 | 1/20 | 0.39 |
| ▸ | CTSK | P43235 | 1/20 | 0.38 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9316061 | 0.88 | BAZ2B (0.45) | CFTRBAZ2BMEN1MAPTMAPK1 | |
| SCHEMBL9315614 | 0.88 | PTGDR2 (0.48) | CFTRBAZ2BMEN1MAPTMAPK1 | |
| SCHEMBL9315615 | 0.88 | PTGDR2 (0.48) | CFTRBAZ2BMEN1MAPTMAPK1 | |
| SCHEMBL9315594 | 0.82 | PARP1 (0.36) | MEN1MAPTKMT2A | |
| SCHEMBL10139841 | 0.81 | CFTR (0.49) | CFTRBAZ2BMEN1MAPTMAPK1 | |
| Hydrochloric Acid SCHEMBL409052 | 0.80 | CFTR (0.51) | CFTRBAZ2BMEN1MAPTMAPK1 | |
| SCHEMBL9315622 | 0.79 | SMN1; SMN2 (0.53) | BAZ2BMEN1MAPTKMT2ASMN1; SMN2 | |
| SCHEMBL9314894 | 0.79 | BAZ2B (0.42) | CFTRBAZ2BMEN1MAPTMAPK1 | |
| SCHEMBL9314846 | 0.77 | BAZ2B (0.46) | CFTRBAZ2BMEN1MAPTMAPK1 | |
| SCHEMBL9314934 | 0.77 | HRH4 (0.41) | CFTRBAZ2BMEN1MAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5281608-A | Antiinflammatory agents and interleukin II antagonist | AMERICAN HOME PRODUCTS CORPORATION (US) | 1994-01-25 | — | — | US | claimed |
| US-5281608-A | Antiinflammatory agents and interleukin II antagonist | AMERICAN HOME PRODUCTS CORPORATION (US) | 1994-01-25 | — | — | US | disclosed |