Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | BAZ2B | Q9UIF8 | 2/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | DPP4 | P27487 | 1/20 | 0.38 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.37 |
| ▸ | CFTR | P13569 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9314894 | 0.84 | BAZ2B (0.42) | BAZ2BMEN1KMT2AMAPTCYP1A2 | |
| SCHEMBL9315614 | 0.84 | PTGDR2 (0.48) | BAZ2BMEN1KMT2AMAPTCYP1A2 | |
| SCHEMBL9315615 | 0.84 | PTGDR2 (0.48) | BAZ2BMEN1KMT2AMAPTCYP1A2 | |
| SCHEMBL9316061 | 0.80 | BAZ2B (0.45) | BAZ2BMEN1KMT2AMAPTCYP1A2 | |
| SCHEMBL9315622 | 0.79 | SMN1; SMN2 (0.53) | L3MBTL1BAZ2BMEN1KMT2AMAPT | |
| SCHEMBL9314695 | 0.78 | TRPV1 (0.47) | BAZ2BMEN1KMT2AMAPTCYP1A2 | |
| SCHEMBL9315820 | 0.78 | MEN1 (0.58) | BAZ2BMEN1KMT2AMAPTCYP1A2 | |
| SCHEMBL9314844 | 0.77 | CFTR (0.42) | BAZ2BMEN1KMT2AMAPTCFTR | |
| SCHEMBL9314846 | 0.77 | BAZ2B (0.46) | BAZ2BMEN1KMT2AMAPTCYP1A2 | |
| SCHEMBL9314877 | 0.76 | KMT2A (0.46) | BAZ2BHDAC6MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5281608-A | Antiinflammatory agents and interleukin II antagonist | AMERICAN HOME PRODUCTS CORPORATION (US) | 1994-01-25 | — | — | US | claimed |
| US-5281608-A | Antiinflammatory agents and interleukin II antagonist | AMERICAN HOME PRODUCTS CORPORATION (US) | 1994-01-25 | — | — | US | disclosed |