Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTPA | P49638 | 2/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | PDE4A | P27815 | 1/20 | 0.44 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.44 |
| ▸ | PSEN1 | P49768 | 10/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9268591 | 0.92 | TTPA (0.43) | TTPAALOX5MEN1KMT2APDE4A | |
| SCHEMBL9312755 | 0.87 | PTGS1 (0.55) | TTPAALOX5PTGS1PTGS2CYP1A2 | |
| SCHEMBL9313511 | 0.86 | MEN1 (0.49) | TTPAALOX5MEN1KMT2APDE4A | |
| SCHEMBL9312819 | 0.85 | MEN1 (0.40) | TTPAALOX5MEN1KMT2APDE4A | |
| SCHEMBL9314035 | 0.83 | TTPA (0.47) | TTPAALOX5MEN1KMT2APDE4A | |
| SCHEMBL9314929 | 0.80 | TTPA (0.46) | TTPAALOX5MEN1KMT2APDE4A | |
| SCHEMBL9312743 | 0.78 | MEN1 (0.33) | MEN1KMT2APDE4APDE3A | |
| SCHEMBL9314914 | 0.78 | PSEN1 (0.52) | TTPAALOX5MEN1KMT2APDE4A | |
| SCHEMBL9314093 | 0.77 | TTPA (0.47) | TTPAALOX5MEN1KMT2APDE4A | |
| SCHEMBL9314872 | 0.76 | TTPA (0.43) | TTPAALOX5MEN1KMT2APDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5315017-A | Peroxidation and eicosanoid biosynthesis inhibition | ADIR ET COMPAGNIE (FR) | 1994-05-24 | — | — | US | disclosed |