Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | BAZ2B | Q9UIF8 | 2/20 | 0.46 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.43 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9315604 | 0.90 | MAPT (0.55) | KMT2AMAPTMEN1TDP1PDGFRB | |
| SCHEMBL9315820 | 0.86 | MEN1 (0.58) | KMT2AMAPTMEN1CYP1A2CYP3A4 | |
| SCHEMBL9314846 | 0.85 | BAZ2B (0.46) | KMT2AMAPTMEN1CYP1A2CYP3A4 | |
| SCHEMBL9314841 | 0.83 | BAZ2B (0.45) | KMT2AMAPTMEN1CYP1A2CYP3A4 | |
| SCHEMBL9315615 | 0.83 | PTGDR2 (0.48) | KMT2AMAPTMEN1CYP1A2CYP3A4 | |
| SCHEMBL9315614 | 0.83 | PTGDR2 (0.48) | KMT2AMAPTMEN1CYP1A2CYP3A4 | |
| SCHEMBL9314695 | 0.81 | TRPV1 (0.47) | KMT2AMAPTMEN1CYP1A2CYP3A4 | |
| SCHEMBL9315622 | 0.80 | SMN1; SMN2 (0.53) | KMT2AMAPTMEN1CYP1A2CYP2D6 | |
| SCHEMBL9315583 | 0.79 | MAPT (0.48) | KMT2AMAPTMEN1CYP1A2CYP3A4 | |
| SCHEMBL9316061 | 0.78 | BAZ2B (0.45) | KMT2AMAPTMEN1CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5281608-A | Antiinflammatory agents and interleukin II antagonist | AMERICAN HOME PRODUCTS CORPORATION (US) | 1994-01-25 | — | — | US | claimed |
| US-5281608-A | Antiinflammatory agents and interleukin II antagonist | AMERICAN HOME PRODUCTS CORPORATION (US) | 1994-01-25 | — | — | US | disclosed |