Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | PDGFRB | P09619 | 4/20 | 0.54 |
| ▸ | POLB | P06746 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | KIT | P10721 | 1/20 | 0.39 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9314877 | 0.90 | KMT2A (0.46) | MAPTTDP1ALDH1A1GAAMAPK1 | |
| SCHEMBL9315583 | 0.87 | MAPT (0.48) | MAPTTDP1ALDH1A1GAAMAPK1 | |
| SCHEMBL9315615 | 0.81 | PTGDR2 (0.48) | MAPTGAAMAPK1MEN1KMT2A | |
| SCHEMBL9315614 | 0.81 | PTGDR2 (0.48) | MAPTGAAMAPK1MEN1KMT2A | |
| SCHEMBL9315820 | 0.80 | MEN1 (0.58) | MAPTGAAMAPK1PDGFRBMEN1 | |
| SCHEMBL9314846 | 0.79 | BAZ2B (0.46) | MAPTALDH1A1GAAMAPK1MEN1 | |
| SCHEMBL9314695 | 0.78 | TRPV1 (0.47) | MAPTALDH1A1GAAMAPK1MEN1 | |
| SCHEMBL9315622 | 0.78 | SMN1; SMN2 (0.53) | MAPTTDP1ALDH1A1GAAPOLB | |
| SCHEMBL9314841 | 0.77 | BAZ2B (0.45) | MAPTALDH1A1GAAMAPK1MEN1 | |
| SCHEMBL9316061 | 0.75 | BAZ2B (0.45) | MAPTTDP1ALDH1A1GAAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5281608-A | Antiinflammatory agents and interleukin II antagonist | AMERICAN HOME PRODUCTS CORPORATION (US) | 1994-01-25 | — | — | US | claimed |
| US-5281608-A | Antiinflammatory agents and interleukin II antagonist | AMERICAN HOME PRODUCTS CORPORATION (US) | 1994-01-25 | — | — | US | disclosed |