Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTPA | P49638 | 2/20 | 0.52 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | PSEN1 | P49768 | 4/20 | 0.42 |
| ▸ | PDE4A | P27815 | 1/20 | 0.41 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9254423 | 0.91 | TTPA (0.47) | TTPAALOX5MEN1KMT2AKDM4E | |
| SCHEMBL9252607 | 0.88 | TTPA (0.57) | TTPAALOX5MEN1KMT2ACYP1A2 | |
| SCHEMBL9312815 | 0.87 | PTGS1 (0.58) | MEN1KMT2AKDM4EMAPTCYP1A2 | |
| SCHEMBL7836851 | 0.85 | TTPA (0.51) | TTPAALOX5MEN1KMT2AMAPT | |
| SCHEMBL9314925 | 0.83 | TTPA (0.51) | TTPAALOX5MEN1KMT2ACYP1A2 | |
| SCHEMBL9250008 | 0.81 | TTPA (0.56) | TTPAALOX5MEN1KMT2ACYP1A2 | |
| SCHEMBL9010322 | 0.80 | TTPA (0.54) | TTPAALOX5MEN1KMT2ACYP1A2 | |
| SCHEMBL9010317 | 0.80 | TTPA (0.54) | TTPAALOX5MEN1KMT2ACYP1A2 | |
| SCHEMBL9655145 | 0.80 | BCHE (0.49) | TTPAALOX5BCHEACHE | |
| SCHEMBL9314876 | 0.79 | TTPA (0.55) | TTPAALOX5MEN1KMT2ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5315017-A | Peroxidation and eicosanoid biosynthesis inhibition | ADIR ET COMPAGNIE (FR) | 1994-05-24 | — | — | US | disclosed |