SCHEMBL9315152

SCHEMBL9315152

CCCCCOc1cccc2c(O)cccc12

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 1/20 0.53
CNR1 P21554 5/20 0.52
CNR2 P34972 5/20 0.52
CYP2C9 P11712 1/20 0.52
MEN1 O00255 2/20 0.48
KMT2A Q03164 2/20 0.48
HTT P42858 1/20 0.48
HTR1B P28222 3/20 0.48
LMNA P02545 2/20 0.46
MAPT P10636 2/20 0.46
NR1I2 O75469 1/20 0.46
CHRM2 P08172 1/20 0.46
CYP3A4 P08684 1/20 0.46
ADRA2A P08913 1/20 0.46
OPRK1 P41145 1/20 0.46
HTR2B P41595 1/20 0.46
SLC6A3 Q01959 1/20 0.46
HDAC6 Q9UBN7 1/20 0.46
THRA P10827 1/20 0.46
THRB P10828 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9578532 0.98 CNR1 (0.53) IDO1CNR1CNR2CYP2C9MEN1
SCHEMBL8746001 0.98 CNR1 (0.53) IDO1CNR1CNR2CYP2C9MEN1
SCHEMBL9353430 0.98 CNR1 (0.53) IDO1CNR1CNR2CYP2C9MEN1
SCHEMBL9697360 0.98 CNR1 (0.53) IDO1CNR1CNR2CYP2C9MEN1
SCHEMBL5596066 0.95 IDO1 (0.54) IDO1CNR1CNR2CYP2C9HTR1B
SCHEMBL30003478 0.90 IDO1 (0.67) IDO1CNR1CNR2CYP2C9MEN1
SCHEMBL8665665 0.90 IDO1 (0.67) IDO1CNR1CNR2CYP2C9MEN1
SCHEMBL991493 0.89 IDO1 (0.56) IDO1CNR1CNR2MEN1KMT2A
SCHEMBL23271770 0.88 IDO1 (0.65) IDO1CNR1CNR2CYP2C9MEN1
SCHEMBL11212682 0.88 IDO1 (0.65) IDO1CNR1CNR2CYP2C9MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0453842-A2 Fluor subsituted derivatives of alpha-(5-aryloxy-naphthalen-1-yloxy)propionic acid BAYER AG (DE) 1991-10-30 EP claimed
EP-0309864-B1 ALPHA-(5-ARYLOXY-NAPHTHALEN-1-YL-OXY)-PROPIONIC-ACID DERIVATIVES BAYER AG (DE) 1991-05-22 EP claimed
US-4994601-A Postemergence herbicides BAYER AKTIENGESELLSCHAFT (DE) 1991-02-19 US claimed
EP-0309864-A1 Alpha-(5-aryloxy-naphthalen-1-yl-oxy)-propionic-acid derivatives BAYER AG (DE) 1989-04-05 EP claimed
JP-5221916-A None JP disclosed
JP-4225938-A None JP disclosed
JP-1113331-A None JP disclosed
US-5300676-A Herbicidal fluorine-substituted alpha-(5-aryloxynaphthalen-1-yl-oxy)-propionic acid derivatives BAYER AKTIENGESELLSCHAFT (DE) 1994-04-05 US disclosed
JP-H05221916-A ALPHA-(5-ARYLOXY-NAPHTHALEN-1-YL-OXY)-CARBOXYLIC ACID DERIVATIVE BAYER AG 1993-08-31 JP disclosed
US-5166402-A Herbicidal α-(5-aryloxy-naphthalen-1-yl-oxy)-propionic acid derivatives BAYER AKTIENGESELLSCHAFT (DE) 1992-11-24 US disclosed
EP-0508263-A2 Derivatives of alpha-(5 aryloxy-1 naphthyloxy)-carboxylic acid BAYER AG (DE) 1992-10-14 EP disclosed
JP-H04225938-A FLUORINE-SUBSTITUTED ALPHA-(5-ARYLOXY-NAPHTHALEN-1-YLOXY)-PROPIONIC ACID DERIVATIVE BAYER AG 1992-08-14 JP disclosed
EP-0453842-A2 Fluor subsituted derivatives of alpha-(5-aryloxy-naphthalen-1-yloxy)propionic acid BAYER AG (DE) 1991-10-30 EP disclosed
EP-0309864-B1 ALPHA-(5-ARYLOXY-NAPHTHALEN-1-YL-OXY)-PROPIONIC-ACID DERIVATIVES BAYER AG (DE) 1991-05-22 EP disclosed
US-4994601-A Postemergence herbicides BAYER AKTIENGESELLSCHAFT (DE) 1991-02-19 US disclosed
JP-H01113331-A ALPHA-(5-ARYLOXYNAPHTHALEN-1-YLOXY)-PROPIONIC ACID DERIVATIVE BAYER AG 1989-05-02 JP disclosed
EP-0309864-A1 Alpha-(5-aryloxy-naphthalen-1-yl-oxy)-propionic-acid derivatives BAYER AG (DE) 1989-04-05 EP disclosed