Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCC9 | O60706 | 13/20 | 0.58 |
| ▸ | ABCC8 | Q09428 | 2/20 | 0.58 |
| ▸ | KCNJ11 | Q14654 | 2/20 | 0.58 |
| ▸ | KCNJ8 | Q15842 | 2/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | ABCB1 | P08183 | 5/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7275528 | 1.00 | ABCC9 (0.58) | ABCC9ABCC8KCNJ11KCNJ8CYP1A2 | |
| SCHEMBL9315187 | 1.00 | ABCC9 (0.58) | ABCC9ABCC8KCNJ11KCNJ8CYP1A2 | |
| SCHEMBL9313835 | 0.89 | ABCC9 (0.58) | ABCC9ABCC8KCNJ11KCNJ8CYP1A2 | |
| SCHEMBL9313841 | 0.89 | ABCC9 (0.58) | ABCC9ABCC8KCNJ11KCNJ8CYP1A2 | |
| SCHEMBL9313830 | 0.89 | ABCC9 (0.58) | ABCC9ABCC8KCNJ11KCNJ8CYP1A2 | |
| SCHEMBL8088708 | 0.87 | ABCC9 (0.55) | ABCC9ABCC8KCNJ11KCNJ8CYP1A2 | |
| SCHEMBL9314126 | 0.86 | ABCC9 (0.57) | ABCC9ABCC8KCNJ11KCNJ8CYP1A2 | |
| SCHEMBL9314135 | 0.86 | ABCC9 (0.57) | ABCC9ABCC8KCNJ11KCNJ8CYP1A2 | |
| SCHEMBL9314132 | 0.86 | ABCC9 (0.57) | ABCC9ABCC8KCNJ11KCNJ8CYP1A2 | |
| SCHEMBL9313729 | 0.85 | ABCC9 (0.56) | ABCC9ABCC8KCNJ11KCNJ8CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5284838-A | Hypotensive agents | ELF SANOFI (FR) | 1994-02-08 | — | — | US | disclosed |
| US-5043352-A | Chroman derivatives for the treatment of depressive states | SANOFI (FR) | 1991-08-27 | — | — | US | disclosed |