Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.40 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31538750 | 1.00 | TSHR (0.49) | TSHRMAPTSMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL9315492 | 0.88 | TSHR (0.46) | TSHRMAPTSMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL6372930 | 0.85 | TSHR (0.54) | TSHRMAPTSMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL31538762 | 0.82 | NPC1 (0.48) | MAPTSMN1; SMN2ALDH1A1LMNANPC1 | |
| SCHEMBL31538752 | 0.80 | MAPT (0.49) | MAPTSMN1; SMN2ALDH1A1LMNANPC1 | |
| SCHEMBL9315516 | 0.80 | MAPT (0.49) | MAPTSMN1; SMN2ALDH1A1LMNANPC1 | |
| SCHEMBL9315666 | 0.74 | TSHR (0.49) | TSHRMAPTSMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL31538757 | 0.74 | TSHR (0.49) | TSHRMAPTSMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL6374669 | 0.73 | TSHR (0.50) | TSHRMAPTSMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL13534537 | 0.71 | MAPT (0.47) | MAPTSMN1; SMN2ALDH1A1LMNANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5310620-A | Alkali-soluble nitrone compounds and contrast enhanced material comprising the same | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1994-05-10 | — | — | US | disclosed |