Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | BCHE | P06276 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.45 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.44 |
| ▸ | CTSL | P07711 | 1/20 | 0.44 |
| ▸ | CTSB | P07858 | 1/20 | 0.44 |
| ▸ | TFEB | P19484 | 1/20 | 0.44 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.44 |
| ▸ | MAOB | P27338 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31538757 | 1.00 | TSHR (0.49) | TSHRNPC1RAB9AMEN1KMT2A | |
| SCHEMBL9316426 | 0.83 | NPC1 (0.50) | NPC1RAB9AMEN1KMT2AMAPT | |
| SCHEMBL31538753 | 0.83 | NPC1 (0.50) | NPC1RAB9AMEN1KMT2AMAPT | |
| SCHEMBL9315739 | 0.81 | MEN1 (0.54) | NPC1RAB9AMEN1KMT2AMAPT | |
| SCHEMBL31538750 | 0.74 | TSHR (0.49) | TSHRNPC1RAB9AMEN1KMT2A | |
| SCHEMBL9315249 | 0.74 | TSHR (0.49) | TSHRNPC1RAB9AMEN1KMT2A | |
| SCHEMBL7972705 | 0.74 | NPC1 (0.57) | NPC1RAB9AMEN1KMT2AMAPT | |
| SCHEMBL9315492 | 0.72 | TSHR (0.46) | TSHRMEN1KMT2AMAPTLMNA | |
| SCHEMBL31538756 | 0.71 | MAPT (0.47) | NPC1RAB9AMEN1KMT2AMAPT | |
| SCHEMBL9315438 | 0.71 | MAPT (0.47) | NPC1RAB9AMEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5310620-A | Alkali-soluble nitrone compounds and contrast enhanced material comprising the same | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1994-05-10 | — | — | US | disclosed |