Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | IDO1 | P14902 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 8/20 | 0.45 |
| ▸ | MEN1 | O00255 | 7/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.45 |
| ▸ | APOBEC3A | P31941 | 2/20 | 0.45 |
| ▸ | APOBEC3G | Q9HC16 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | AXL | P30530 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16065331 | 0.81 | ALDH1A1 (0.49) | ALDH1A1HPGDMAPTMEN1KMT2A | |
| SCHEMBL6226010 | 0.81 | ALDH1A1 (0.50) | ALDH1A1HPGDMAPTMEN1KMT2A | |
| SCHEMBL9959635 | 0.80 | ALDH1A1 (0.47) | ALDH1A1HPGDMAPTMEN1KMT2A | |
| SCHEMBL296452 | 0.79 | KDR (0.53) | ALDH1A1HPGDAXLKDR | |
| SCHEMBL16818973 | 0.79 | ALDH1A1 (0.46) | ALDH1A1HPGDMAPTMEN1KMT2A | |
| SCHEMBL9314516 | 0.77 | KDM4E (0.60) | ALDH1A1HPGDIDO1MAPTMEN1 | |
| SCHEMBL6599588 | 0.76 | IDO1 (0.55) | ALDH1A1HPGDIDO1MAPTMEN1 | |
| SCHEMBL15704593 | 0.75 | ALDH1A1 (0.43) | ALDH1A1HPGDMAPTMEN1KMT2A | |
| SCHEMBL29445933 | 0.74 | MEN1 (0.54) | ALDH1A1HPGDMAPTMEN1KMT2A | |
| SCHEMBL317551 | 0.74 | MEN1 (0.54) | ALDH1A1HPGDMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5354870-A | Hair dyes | L'OREAL (FR) | 1994-10-11 | — | — | US | disclosed |
| US-5131911-A | Hair dyes | L'OREAL (FR) | 1992-07-21 | — | — | US | disclosed |
| EP-0428441-A2 | Keratinic fibre dyeing compostions containing oxydation dye precursors and derivatives of 4-hydroxyindole as couplers, and dyeing process using same | L'OREAL (FR) | 1991-05-22 | — | — | EP | disclosed |