Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6259993 | 0.97 | ALDH1A1 (0.53) | ALDH1A1TSHRMAPK1MEN1KMT2A | |
| SCHEMBL6257984 | 0.91 | ALDH1A1 (0.47) | ALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL11134290 | 0.90 | ALDH1A1 (0.53) | ALDH1A1 | |
| SCHEMBL3510739 | 0.89 | TSHR (0.53) | ALDH1A1TSHRMAPK1MEN1KMT2A | |
| SCHEMBL28887397 | 0.89 | ALDH1A1 (0.45) | ALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL24040335 | 0.87 | ALDH1A1 (0.43) | ALDH1A1 | |
| SCHEMBL881157 | 0.85 | — | — | |
| SCHEMBL11136852 | 0.85 | — | — | |
| Hydrochloric Acid SCHEMBL3507061 | 0.84 | ALDH1A1 (0.41) | ALDH1A1 | |
| SCHEMBL31267570 | 0.83 | ALDH1A1 (0.45) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110498757-B | Synthesis method of metal-free 3-acyl indole compound | 中国科学院兰州化学物理研究所 | 2022-03-15 | — | — | CN | disclosed |
| CN-108473623-B | Process for producing vinyl ether polymer having hydroxyl group in side chain and temperature-responsive polymer mixture | 丸善石油化学株式会社 | 2020-12-08 | — | — | CN | disclosed |
| US-5374643-A | Aryl urea (thiourea) and cyanoguanidine derivatives | E. R. SQUIBB & SONS, INC. (US) | 1994-12-20 | — | — | US | disclosed |
| EP-0587180-A2 | Aryl urea (Thiourea) and cyanoguanidine derivatives | E.R. SQUIBB & SONS, INC. (US) | 1994-03-16 | — | — | EP | disclosed |
| US-4950674-A | Arylalkylheterocyclic amines,N-substituted by aryloxyalkyl group in a method for allergy treatment | A. H. ROBINS COMPANY, INCORPORATED (US) | 1990-08-21 | — | — | US | disclosed |
| US-4935421-A | ADRENERGIC BLOCKING AGENTS; GLAUCOMA TREATMENT | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1990-06-19 | — | — | US | disclosed |
| US-4927837-A | TREATMENT OF ALZHEIMER'S DISEASE, SENILE DEMENTIA, OR MEMORY DISORDERS IN THE AGED | ROUSSEL UCLAF (FR) | 1990-05-22 | — | — | US | disclosed |
| US-4859698-A | CARDIOVASCULAR DISORDERS, HYPERLIPIDAEMIAS, HYPERLIPOPROTEINAEMIAS/ | SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. (IT) | 1989-08-22 | — | — | US | disclosed |
| US-4810717-A | ADRENERGIC BLOCKING AGENTS, GLAUCOMA | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1989-03-07 | — | — | US | disclosed |
| US-4798892-A | ADRENERGIC BLOCKING AGENTS, GLAUCOMA | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1989-01-17 | — | — | US | disclosed |
| WO-1983001770-A1 | 2-HYDROXYPROPYLAMINE ARYL ESTER DERIVATIVES | AMERICAN HOSPITAL SUPPLY CORP (US) | 1983-05-26 | — | — | WO | disclosed |
| EP-0009655-B1 | 6-AMINO SUBSTITUTED N-PYRROLYL-3-PYRIDAZINE AMINES, THEIR PREPARATION, AND PHARMACEUTICALLY ANTIHYPERTENSIVE COMPOSITIONS CONTAINING THEM | GRUPPO LEPETIT S.P.A. (IT) | 1983-05-11 | — | — | EP | disclosed |
| EP-0053015-A1 | 1-Phenylthio-2-aminopropane derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1982-06-02 | — | — | EP | disclosed |
| US-4247551-A | N-Pyrrolyl-pyridazineamines and their use as antihypertensive agents | GRUPPO LEPETIT S.P.A. (IT) | 1981-01-27 | — | — | US | disclosed |
| US-4227006-A | ANTITHROMBOTICS | MITSUBISHI CHEMICAL INDUSTRIES LTD. (JP) | 1980-10-07 | — | — | US | disclosed |
| EP-0009655-A1 | 6-Amino substituted N-pyrrolyl-3-pyridazine amines, their preparation, and pharmaceutically antihypertensive compositions containing them | GRUPPO LEPETIT S.P.A. (IT) | 1980-04-16 | — | — | EP | disclosed |
| US-4182706-A | Flame-retardant agents for phenolic resins and process for their production | CHEMISCHE FABRIK KALK GMBH (DE) | 1980-01-08 | — | — | US | disclosed |
| US-4013643-A | N,N-DISUBSTITUTED 2,3-DIPHENYLALLYLAMINES | G. D. SEARLE & CO. (US) | 1977-03-22 | — | — | US | disclosed |
| US-3978045-A | ANTITHROMBOTIC AGENTS | MITSUBISHI CHEMICAL INDUSTRIES LTD. (JA) | 1976-08-31 | — | — | US | disclosed |
| US-3969468-A | 2-Amino-1,2,3,4-tetrahydronaphthalene derivatives | KYOWA HAKKO KOGYO CO., LTD. (JA) | 1976-07-13 | — | — | US | disclosed |