Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 9/20 | 0.82 |
| ▸ | DRD3 | P35462 | 7/20 | 0.82 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.67 |
| ▸ | DRD4 | P21917 | 6/20 | 0.56 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.55 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.55 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.55 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.50 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL895742 | 0.90 | DRD2 (1.00) | DRD2DRD3ADRA1ADRD4CHRM2 | |
| SCHEMBL43366 | 0.90 | DRD2 (1.00) | DRD2DRD3ADRA1ADRD4CHRM2 | |
| SCHEMBL29429678 | 0.90 | DRD2 (1.00) | DRD2DRD3ADRA1ADRD4CHRM2 | |
| SCHEMBL895845 | 0.90 | DRD2 (1.00) | DRD2DRD3ADRA1ADRD4CHRM2 | |
| SCHEMBL29547385 | 0.90 | DRD2 (1.00) | DRD2DRD3ADRA1ADRD4CHRM2 | |
| Hydrochloric Acid SCHEMBL3468007 | 0.89 | DRD2 (0.97) | DRD2DRD3ADRA1ADRD4CHRM2 | |
| Hydrochloric Acid SCHEMBL31672141 | 0.89 | DRD2 (0.97) | DRD2DRD3ADRA1ADRD4CHRM2 | |
| Hydrochloric Acid SCHEMBL6824058 | 0.89 | DRD2 (0.97) | DRD2DRD3ADRA1ADRD4CHRM2 | |
| Hydrochloric Acid SCHEMBL6824054 | 0.89 | DRD2 (0.97) | DRD2DRD3ADRA1ADRD4CHRM2 | |
| SCHEMBL4210081 | 0.82 | DRD2 (0.79) | DRD2DRD3ADRA1ACHRM2CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0583485-A1 | ETHANOLAMINE DERIVATIVES HAVING SYMPATHOMIMETIC AND ANTI-POLLAKIURIA ACTIVITIES. | FUJISAWA PHARMACEUTICAL CO (JP) | 1994-02-23 | — | — | EP | disclosed |