Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAF1 | P04049 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10025189 | 0.85 | KMT2A (0.64) | RAF1KMT2AL3MBTL1KDM4ELMNA | |
| SCHEMBL9315993 | 0.84 | RAF1 (0.56) | RAF1KMT2AL3MBTL1KDM4ELMNA | |
| SCHEMBL9771702 | 0.83 | RAF1 (0.52) | RAF1KMT2AL3MBTL1KDM4ELMNA | |
| SCHEMBL16173948 | 0.82 | KMT2A (0.60) | RAF1KMT2AL3MBTL1KDM4ELMNA | |
| Hydrochloric Acid SCHEMBL9314791 | 0.82 | RAF1 (0.51) | RAF1KMT2AL3MBTL1KDM4ELMNA | |
| SCHEMBL1439664 | 0.77 | MAPT (0.51) | L3MBTL1KDM4ESMN1; SMN2SIGMAR1ALDH1A1 | |
| SCHEMBL941088 | 0.75 | KMT2A (0.54) | RAF1KMT2AL3MBTL1KDM4ELMNA | |
| SCHEMBL11108445 | 0.75 | KMT2A (0.58) | RAF1KMT2AL3MBTL1KDM4ELMNA | |
| SCHEMBL20346359 | 0.74 | POLQ (0.47) | KMT2AL3MBTL1LMNAALDH1A1MAPT | |
| SCHEMBL556208 | 0.73 | KMT2A (0.53) | RAF1KMT2AL3MBTL1KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5300527-A | Administering anticholinergic agents for treating the memory dysfunction | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1994-04-05 | — | — | US | disclosed |
| US-5177111-A | Analgesic | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1993-01-05 | — | — | US | disclosed |
| EP-0432719-A1 | Alkylamino- and alkylaminoalkyl diarylketones, a process for their preparation and their use as medicaments | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1991-06-19 | — | — | EP | disclosed |