Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAF1 | P04049 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | ABL1 | P00519 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10025189 | 0.86 | KMT2A (0.64) | RAF1KMT2AL3MBTL1POLBKDM4E | |
| SCHEMBL6359073 | 0.86 | CTBP2 (0.54) | KMT2AL3MBTL1CTBP2POLBHPGD | |
| SCHEMBL9315566 | 0.84 | RAF1 (0.55) | RAF1KMT2AL3MBTL1POLBKDM4E | |
| SCHEMBL9771702 | 0.84 | RAF1 (0.52) | RAF1KMT2AL3MBTL1CTBP2KDM4E | |
| SCHEMBL16173948 | 0.83 | KMT2A (0.60) | RAF1KMT2AL3MBTL1KDM4ELMNA | |
| Hydrochloric Acid SCHEMBL9314791 | 0.83 | RAF1 (0.51) | RAF1KMT2AL3MBTL1CTBP2KDM4E | |
| SCHEMBL165944 | 0.81 | CTBP2 (0.57) | KMT2AL3MBTL1CTBP2POLBLMNA | |
| SCHEMBL3280980 | 0.79 | KCNK3 (0.51) | KMT2AL3MBTL1CTBP2POLBKDM4E | |
| SCHEMBL3289372 | 0.78 | L3MBTL1 (0.58) | KMT2AL3MBTL1POLBKDM4ELMNA | |
| SCHEMBL2477387 | 0.78 | NPC1 (0.57) | KMT2AL3MBTL1CTBP2POLBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5300527-A | Administering anticholinergic agents for treating the memory dysfunction | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1994-04-05 | — | — | US | disclosed |
| US-5177111-A | Analgesic | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1993-01-05 | — | — | US | disclosed |
| EP-0432719-A1 | Alkylamino- and alkylaminoalkyl diarylketones, a process for their preparation and their use as medicaments | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1991-06-19 | — | — | EP | disclosed |
| US-5006563-A | Alzheimer's disease | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1991-04-09 | — | — | US | disclosed |