Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.56 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.49 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.41 |
| ▸ | ALPL | P05186 | 1/20 | 0.40 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | LIPA | P38571 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | FPR3 | P25089 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9797958 | 0.89 | EPHX1 (0.43) | EPHX1EPHX2MTNR1AMTNR1BHSD11B1 | |
| SCHEMBL224441 | 0.84 | — | — | |
| SCHEMBL14242712 | 0.83 | EPHX1 (0.58) | EPHX1EPHX2MTNR1AMTNR1BHSD11B1 | |
| SCHEMBL4078312 | 0.81 | EPHX1 (0.56) | EPHX1EPHX2HSD11B1KMT2ASMN1; SMN2 | |
| SCHEMBL7753207 | 0.79 | EPHX1 (0.53) | EPHX1EPHX2 | |
| SCHEMBL11625924 | 0.79 | EPHX1 (0.52) | EPHX1MTNR1AMTNR1BLMNASMN1; SMN2 | |
| SCHEMBL473462 | 0.77 | EPHX1 (0.50) | EPHX1EPHX2MTNR1AMTNR1BKMT2A | |
| SCHEMBL473460 | 0.77 | EPHX1 (0.50) | EPHX1EPHX2MTNR1AMTNR1BKMT2A | |
| SCHEMBL6645772 | 0.77 | MEN1 (0.54) | EPHX1EPHX2KMT2ASMN1; SMN2HPGD | |
| SCHEMBL4078313 | 0.77 | EPHX1 (0.51) | EPHX1EPHX2KMT2ASMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011000945-A9 | AMINOALKAMIDES FOR USE IN THE TREATMENT OF INFLAMMATORY, DEGENERATIVE OR DEMYELINATING DISEASES OF THE CNS | NENSIUS RESEARCH A/S (DK) | 2011-04-07 | — | — | WO | disclosed |
| WO-2011000945-A2 | AMINOALKAMIDES FOR USE IN THE TREATMENT OF INFLAMMATORY, DEGENERATIVE OR DEMYELINATING DISEASES OF THE CNS | NENSIUS RESEARCH A/S (DK) | 2011-01-06 | — | — | WO | disclosed |