Ciaftalan

Ciaftalan

SCHEMBL9315644

[Gd].c1ccc2c(c1)-c1nc-2nc2[nH]c(nc3nc(nc4[nH]c(n1)c1ccccc41)-c1ccccc1-3)c1ccccc21.c1ccc2c(c1)-c1nc-2nc2[nH]c(nc3nc(nc4[nH]c(n1)c1ccccc41)-c1ccccc1-3)c1ccccc21

nearest known ligand 0.45

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 4/20 0.45
MEN1 O00255 4/20 0.45
KMT2A Q03164 4/20 0.45
RECQL P46063 2/20 0.45
THRB P10828 1/20 0.45
APEX1 P27695 1/20 0.45
BLM P54132 1/20 0.45
CA5A P35218 1/20 0.40
KDM4E B2RXH2 4/20 0.37
HSD17B10 Q99714 5/20 0.35
CYP1A2 P05177 3/20 0.35
CYP3A4 P08684 3/20 0.35
CYP2D6 P10635 3/20 0.35
CYP2C19 P33261 3/20 0.35
USP2 O75604 1/20 0.35
ALOX15 P16050 1/20 0.35
CLK4 Q9HAZ1 1/20 0.35
ALDH1A1 P00352 5/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
MAPK1 P28482 4/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ciaftalan SCHEMBL2206040 1.00 TDP1 (0.45) TDP1MEN1KMT2ARECQLTHRB
Ciaftalan SCHEMBL15816 0.98 MEN1 (0.46) TDP1MEN1KMT2ARECQLTHRB
SCHEMBL813083 0.98 MEN1 (0.46) TDP1MEN1KMT2ARECQLTHRB
Ciaftalan SCHEMBL29356273 0.98 MEN1 (0.46) TDP1MEN1KMT2ARECQLTHRB
Ciaftalan SCHEMBL1728179 0.98 MEN1 (0.46) TDP1MEN1KMT2ARECQLTHRB
Ciaftalan SCHEMBL5795179 0.98 MEN1 (0.46) TDP1MEN1KMT2ARECQLTHRB
Ciaftalan SCHEMBL29360952 0.98 MEN1 (0.46) TDP1MEN1KMT2ARECQLTHRB
Ciaftalan SCHEMBL7996593 0.96 MEN1 (0.46) TDP1MEN1KMT2ARECQLTHRB
Ciaftalan SCHEMBL181789 0.96 MEN1 (0.45) TDP1MEN1KMT2ARECQLTHRB
Ciaftalan SCHEMBL223248 0.96 MEN1 (0.45) TDP1MEN1KMT2ARECQLTHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5202786-A Spaced apart partially reflecting mirrors having cavity between filled with solutions of rare earth bis-phthalocyanine to control intensity and wavelength of light transmitted THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 1993-04-13 US claimed
US-5350459-A Organic photovoltaic element RICOH COMPANY, LTD. (JP) 1994-09-27 US disclosed