Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | NAAA | Q02083 | 1/20 | 0.36 |
| ▸ | PTPN7 | P35236 | 4/20 | 0.35 |
| ▸ | HMGCR | P04035 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | DNM1 | Q05193 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3897705 | 1.00 | TSHR (0.42) | TSHRTHRBNAAAPTPN7HMGCR | |
| SCHEMBL10717466 | 1.00 | TSHR (0.42) | TSHRTHRBNAAAPTPN7HMGCR | |
| SCHEMBL27710723 | 1.00 | TSHR (0.42) | TSHRTHRBNAAAPTPN7HMGCR | |
| SCHEMBL8187522 | 1.00 | TSHR (0.42) | TSHRTHRBNAAAPTPN7HMGCR | |
| SCHEMBL8187524 | 1.00 | TSHR (0.42) | TSHRTHRBNAAAPTPN7HMGCR | |
| SCHEMBL3897707 | 1.00 | TSHR (0.42) | TSHRTHRBNAAAPTPN7HMGCR | |
| SCHEMBL10717470 | 1.00 | TSHR (0.42) | TSHRTHRBNAAAPTPN7HMGCR | |
| SCHEMBL8750140 | 0.97 | — | — | |
| SCHEMBL3899481 | 0.89 | — | — | |
| SCHEMBL23647759 | 0.82 | TSHR (0.44) | TSHRTHRBHMGCRDNM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0576605-A4 | COMPOSITIONS AND METHOD COMPRISING AMINOALCOHOL DERIVATIVES AS MEMBRANE PENETRATION ENHANCERS | RAJADHYAKSHA VITHAL J (US) | 1994-06-08 | — | — | EP | disclosed |
| EP-0576605-A1 | COMPOSITIONS AND METHOD COMPRISING AMINOALCOHOL DERIVATIVES AS MEMBRANE PENETRATION ENHANCERS | THERAPEUTIC PATCH RESEARCH N.V. (US) | 1994-01-05 | — | — | EP | disclosed |
| WO-1992016236-A1 | COMPOSITIONS AND METHOD COMPRISING AMINOALCOHOL DERIVATIVES AS MEMBRANE PENETRATION ENHANCERS | RAJADHYAKSHA VITHAL J (US) | 1992-10-01 | — | — | WO | disclosed |