Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IGF1R | P08069 | 12/20 | 0.55 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4466085 | 0.72 | IGF1R (1.00) | IGF1R | |
| SCHEMBL8071869 | 0.71 | HRH4 (0.61) | HRH4CYP2D6CYP2C19ALDH1A1SMN1; SMN2 | |
| SCHEMBL12439820 | 0.71 | IGF1R (0.58) | IGF1REPHX2 | |
| SCHEMBL18884429 | 0.71 | EPHX2 (0.48) | IGF1RALDH1A1SMN1; SMN2EPHX2 | |
| SCHEMBL14311612 | 0.70 | IGF1R (0.59) | IGF1REPHX2 | |
| SCHEMBL6402251 | 0.69 | NPC1 (0.54) | IGF1RALDH1A1SMN1; SMN2EPHX2 | |
| SCHEMBL1318375 | 0.69 | CYP2D6 (0.64) | HRH4CYP2D6CYP2C19ALDH1A1SMN1; SMN2 | |
| SCHEMBL12852537 | 0.69 | EPHX2 (0.49) | IGF1RALDH1A1SMN1; SMN2EPHX2 | |
| SCHEMBL745934 | 0.69 | ALDH1A1 (0.49) | IGF1RALDH1A1SMN1; SMN2EPHX2 | |
| SCHEMBL1790427 | 0.68 | ALDH1A1 (0.36) | IGF1RCYP2D6ALDH1A1SMN1; SMN2EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5280009-A | Herbicide | BASF AKTIENGESELLSCHAFT (DE) | 1994-01-18 | — | — | US | disclosed |
| EP-0523533-A1 | Substituted pyrimidin derivatives and their use for combatting the growth of undesirable plants | BASF Aktiengesellschaft (DE) | 1993-01-20 | — | — | EP | disclosed |