Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 2/20 | 0.51 |
| ▸ | PRKCA | P17252 | 6/20 | 0.48 |
| ▸ | DGKA | P23743 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 4/20 | 0.41 |
| ▸ | CNR1 | P21554 | 2/20 | 0.41 |
| ▸ | CNR2 | P34972 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8970473 | 0.88 | NAAA (0.51) | NAAAPRKCADGKALMNATRPV1 | |
| SCHEMBL8969242 | 0.88 | NAAA (0.51) | NAAAPRKCADGKALMNATRPV1 | |
| SCHEMBL8970915 | 0.88 | NAAA (0.51) | NAAAPRKCADGKALMNATRPV1 | |
| SCHEMBL8970774 | 0.88 | NAAA (0.51) | NAAAPRKCADGKALMNATRPV1 | |
| SCHEMBL8970291 | 0.86 | NAAA (0.49) | NAAAPRKCADGKALMNATRPV1 | |
| SCHEMBL8970369 | 0.81 | NAAA (0.42) | NAAAPRKCADGKA | |
| SCHEMBL20026410 | 0.80 | CHRM2 (0.39) | — | |
| SCHEMBL4941578 | 0.78 | NAAA (0.68) | NAAAPRKCADGKALMNA | |
| SCHEMBL25682116 | 0.78 | NAAA (0.54) | NAAAPRKCADGKALMNATRPV1 | |
| SCHEMBL28158465 | 0.76 | NAAA (0.66) | NAAAPRKCADGKALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5318987-A | Used for prophylaxis and treats coronary, circulatory and vascular diseases | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-06-07 | — | — | US | disclosed |