Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 1/20 | 0.33 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.33 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4888186 | 0.81 | TDP1 (0.40) | PRSS1PRSS2PRSS3 | |
| SCHEMBL8767493 | 0.75 | IDO1 (0.41) | — | |
| SCHEMBL78987 | 0.72 | SIGMAR1 (0.44) | PRSS1PRSS2PRSS3 | |
| SCHEMBL11408727 | 0.72 | SCN2A (0.32) | — | |
| SCHEMBL636848 | 0.71 | TDP1 (0.35) | PRSS1PRSS2PRSS3 | |
| SCHEMBL9317579 | 0.71 | SIGMAR1 (0.38) | — | |
| Hydrochloric Acid SCHEMBL9316439 | 0.71 | SIGMAR1 (0.40) | PRSS1PRSS2PRSS3 | |
| SCHEMBL29768251 | 0.71 | ESR1 (0.40) | — | |
| SCHEMBL22292617 | 0.71 | ESR1 (0.40) | — | |
| Hydrochloric Acid SCHEMBL8745417 | 0.71 | SIGMAR1 (0.43) | PRSS1PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0532642-A4 | — | — | 1994-04-27 | — | — | EP | disclosed |
| EP-0532642-A1 | SUBSTITUTED GUANIDINES HAVING HIGH BINDING TO THE SIGMA RECEPTOR AND THE USE THEREOF | STATE OF OREGON, acting through OREGON STATE BOARD OF HIGHER EDUCATION, acting for OREGON HEALTH SC. UNIV. AND UNIV. OF OREGON (US) | 1993-03-24 | — | — | EP | disclosed |
| WO-1991018868-A1 | SUBSTITUTED GUANIDINES HAVING HIGH BINDING TO THE SIGMA RECEPTOR AND THE USE THEREOF | STATE OF OREGON, acting by and through the OREGON STATE BOARD OF HIGHER EDUCATION, acting for and onbehalf of the OREGON HEALTH SCIENCES UNIVERSITY (US) | 1991-12-12 | — | — | WO | disclosed |