Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 16/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.35 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.35 |
| ▸ | SCN1A | P35498 | 1/20 | 0.34 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.34 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9316066 | 0.90 | ABCB1 (0.34) | ABCB1ALDH1A1CYP1A2CYP2D6MAPT | |
| SCHEMBL9316090 | 0.80 | ABCB1 (0.66) | ABCB1SCN1ASCN2ASCN3A | |
| SCHEMBL9317588 | 0.75 | ABCB1 (0.55) | ABCB1ALDH1A1CYP1A2CYP2D6NPSR1 | |
| SCHEMBL1669812 | 0.74 | ABCB1 (0.74) | ABCB1CYP1A2CYP2D6NPSR1TSHR | |
| Hydrochloric Acid SCHEMBL10830495 | 0.74 | MEN1 (0.55) | ABCB1ALDH1A1CYP1A2CYP2D6NPSR1 | |
| SCHEMBL9316688 | 0.70 | ABCB1 (0.49) | ABCB1ALDH1A1MAPTSCN1ASCN2A | |
| SCHEMBL7266813 | 0.69 | SCN1A (0.60) | ALDH1A1CYP1A2CYP2D6MAPTSCN1A | |
| SCHEMBL27894245 | 0.69 | PTGER1 (0.47) | ALDH1A1MAPT | |
| SCHEMBL9316096 | 0.67 | ABCB1 (0.41) | ABCB1ALDH1A1CYP1A2CYP2D6NPSR1 | |
| Hydrochloric Acid SCHEMBL9316740 | 0.67 | MEN1 (0.42) | ABCB1ALDH1A1CYP1A2CYP2D6NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0462150-B1 | NOVEL ARYLOXY ALKYL AMINES, THEIR PRODUCTION AND MEDICAMENTS CONTAINING THEM | LAEVOSAN GMBH & CO KG (AT) | 1994-09-07 | — | — | EP | disclosed |
| US-5334602-A | Antiarrhytmic agent | LAEVOSAN-GESELLSCHAFT GMBH (AT) | 1994-08-02 | — | — | US | disclosed |