Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 12/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.54 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.54 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.54 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.54 |
| ▸ | KCNK2 | O95069 | 1/20 | 0.54 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.54 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.54 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.54 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.54 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.54 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.54 |
| ▸ | HTR2A | P28223 | 1/20 | 0.54 |
| ▸ | HTR2C | P28335 | 1/20 | 0.54 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10830495 | 0.99 | MEN1 (0.55) | ABCB1LMNACYP1A2CYP2D6CYP3A4 | |
| SCHEMBL9316096 | 0.87 | ABCB1 (0.41) | ABCB1LMNACYP1A2CYP2D6CYP3A4 | |
| Hydrochloric Acid SCHEMBL9316740 | 0.86 | MEN1 (0.42) | ABCB1LMNACYP1A2CYP2D6CYP3A4 | |
| SCHEMBL9316090 | 0.81 | ABCB1 (0.66) | ABCB1 | |
| SCHEMBL9316252 | 0.75 | ABCB1 (0.42) | ABCB1CYP1A2CYP2D6ADRB2ADRB1 | |
| SCHEMBL27894245 | 0.74 | PTGER1 (0.47) | LMNASMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL11922778 | 0.71 | MEN1 (0.68) | ABCB1LMNACYP1A2CYP2D6SMN1; SMN2 | |
| SCHEMBL8366529 | 0.71 | CYP1A2 (0.42) | LMNACYP1A2ADRB2ADRB1TSHR | |
| SCHEMBL11111584 | 0.71 | ABCB1 (0.55) | ABCB1LMNACYP1A2CYP2D6CYP3A4 | |
| SCHEMBL9316688 | 0.71 | ABCB1 (0.49) | ABCB1SMN1; SMN2ADRA2CALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0462150-B1 | NOVEL ARYLOXY ALKYL AMINES, THEIR PRODUCTION AND MEDICAMENTS CONTAINING THEM | LAEVOSAN GMBH & CO KG (AT) | 1994-09-07 | — | — | EP | disclosed |
| US-5334602-A | Antiarrhytmic agent | LAEVOSAN-GESELLSCHAFT GMBH (AT) | 1994-08-02 | — | — | US | disclosed |