Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.62 |
| ▸ | LMNA | P02545 | 3/20 | 0.62 |
| ▸ | TOP2A | P11388 | 3/20 | 0.62 |
| ▸ | TOP2B | Q02880 | 3/20 | 0.62 |
| ▸ | HPGD | P15428 | 2/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.62 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | PIK3CG | P48736 | 6/20 | 0.57 |
| ▸ | PIK3CD | O00329 | 4/20 | 0.54 |
| ▸ | PIK3R1 | P27986 | 4/20 | 0.54 |
| ▸ | PIK3CA | P42336 | 4/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9757383 | 0.88 | KDM4E (0.69) | KDM4EALDH1A1LMNATOP2ATOP2B | |
| SCHEMBL9650948 | 0.88 | KDM4E (0.48) | KDM4EALDH1A1LMNATOP2ATOP2B | |
| SCHEMBL9316471 | 0.84 | PIK3CG (0.65) | KDM4EALDH1A1LMNATOP2ATOP2B | |
| SCHEMBL9757674 | 0.84 | PIK3CG (0.67) | KDM4EALDH1A1LMNATOP2ATOP2B | |
| SCHEMBL9316333 | 0.82 | TOP2A (0.64) | KDM4EALDH1A1TOP2ATOP2BHPGD | |
| SCHEMBL9316567 | 0.82 | DPP4 (0.59) | KDM4ELMNATOP2ATOP2BHSD17B10 | |
| SCHEMBL9757492 | 0.82 | KDM4E (0.63) | KDM4EALDH1A1LMNATOP2ATOP2B | |
| SCHEMBL31157349 | 0.81 | LMNA (0.58) | KDM4EALDH1A1LMNATOP2ATOP2B | |
| Hydrochloric Acid SCHEMBL9757445 | 0.81 | KDM4E (0.59) | KDM4EALDH1A1LMNATOP2ATOP2B | |
| SCHEMBL6310301 | 0.80 | KDM4E (0.67) | KDM4EALDH1A1LMNATOP2ATOP2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5371090-A | Bactericides, feed additives | BAYER AKTIENGESELLSCHAFT (DE) | 1994-12-06 | — | — | US | disclosed |
| US-5312823-A | Antibacterials | BAYER AKTIENGESELLSCHAFT (DE) | 1994-05-17 | — | — | US | disclosed |
| CN-1068114-A | 7-azepine iso-dihydro-indole-group-quinolone and naphthyridonecarboxylic derivative | BAYER AG (DE) | 1993-01-20 | — | — | CN | disclosed |
| EP-0520277-A2 | 7-Azaisoindolinyl-quinolone- and naphthyridoncarboxylic acid derivatives | BAYER AG (DE) | 1992-12-30 | — | — | EP | disclosed |