Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOAT1 | P35610 | 6/20 | 0.43 |
| ▸ | SOAT2 | O75908 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9315916 | 0.77 | SLC6A3 (0.39) | SMN1; SMN2ALDH1A1KDM4ESLC6A3 | |
| SCHEMBL9316545 | 0.77 | MEN1 (0.45) | SOAT1KMT2AMEN1TDP1SMN1; SMN2 | |
| SCHEMBL5929952 | 0.67 | MEN1 (0.40) | KMT2AMEN1ALDH1A1SLC6A3 | |
| SCHEMBL9316323 | 0.66 | SOAT1 (0.67) | SOAT1SOAT2KMT2AMEN1TDP1 | |
| SCHEMBL9843936 | 0.66 | SMN1; SMN2 (0.77) | SOAT1SOAT2KMT2AMEN1TDP1 | |
| SCHEMBL5689417 | 0.65 | SLC6A3 (0.42) | KMT2AMEN1LMNASLC6A3 | |
| SCHEMBL9316603 | 0.65 | SOAT1 (0.58) | SOAT1SOAT2KMT2AMEN1TDP1 | |
| SCHEMBL2148218 | 0.65 | SMN1; SMN2 (0.70) | SOAT1SOAT2KMT2AMEN1TDP1 | |
| SCHEMBL5686699 | 0.65 | SLC6A3 (0.45) | KMT2AMEN1SLC6A3 | |
| SCHEMBL5570411 | 0.65 | MEN1 (0.40) | KMT2AMEN1TDP1ALDH1A1SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5278326-A | Aromatic | WARNER-LAMBERT COMPANY (US) | 1994-01-11 | — | — | US | disclosed |