Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.34 |
| ▸ | RNASEL | Q05823 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 6/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10622027 | 0.81 | TSHR (0.46) | TSHRALDH1A1HPGDATMTGFBR1 | |
| SCHEMBL7889401 | 0.79 | TSHR (0.51) | TSHRALDH1A1HPGDATMLMNA | |
| SCHEMBL9321557 | 0.79 | TSHR (0.40) | TSHRALDH1A1HPGDATMTGFBR1 | |
| SCHEMBL1132239 | 0.79 | TSHR (0.40) | TSHRALDH1A1HPGDATMTGFBR1 | |
| SCHEMBL27567837 | 0.78 | TSHR (0.44) | TSHRALDH1A1HPGDATMTGFBR1 | |
| SCHEMBL18660317 | 0.78 | TSHR (0.41) | TSHRALDH1A1HPGDATMTGFBR1 | |
| SCHEMBL9316633 | 0.77 | TSHR (0.42) | TSHRALDH1A1HPGDATMTGFBR1 | |
| SCHEMBL7171607 | 0.76 | TSHR (0.38) | TSHRALDH1A1HPGDATMTGFBR1 | |
| SCHEMBL7172656 | 0.76 | TSHR (0.38) | TSHRALDH1A1HPGDATMTGFBR1 | |
| SCHEMBL2528974 | 0.76 | TSHR (0.38) | TSHRALDH1A1HPGDATMTGFBR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5369204-A | Low molecular weight acrylamidoglycolate crosslinker and process | CYTEC TECHNOLOGY CORP. (US) | 1994-11-29 | — | — | US | disclosed |
| US-4760168-A | Preparation of alkyl acrylamidoglycolates and their alkyl ethers | AMERICAN CYANAMID COMPANY (US) | 1988-07-26 | — | — | US | disclosed |