Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | PLA2G2C | Q5R387 | 4/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | CES2 | O00748 | 1/20 | 0.34 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10622027 | 0.95 | TSHR (0.46) | TSHRALDH1A1MAPTHPGDATM | |
| SCHEMBL7889404 | 0.79 | TSHR (0.49) | TSHRALDH1A1MAPTHSD17B10HPGD | |
| SCHEMBL9316631 | 0.77 | TSHR (0.44) | TSHRALDH1A1HPGDATMTGFBR1 | |
| SCHEMBL27567837 | 0.77 | TSHR (0.44) | TSHRALDH1A1HPGDPLA2G2CATM | |
| SCHEMBL27019 | 0.75 | TSHR (0.43) | TSHRALDH1A1MAPTHSD17B10HPGD | |
| SCHEMBL28509952 | 0.75 | TSHR (0.43) | TSHRALDH1A1MAPTHSD17B10HPGD | |
| SCHEMBL10626213 | 0.75 | MAPT (0.43) | TSHRALDH1A1MAPTHSD17B10HPGD | |
| SCHEMBL1132239 | 0.74 | TSHR (0.40) | TSHRALDH1A1HPGDPLA2G2CATM | |
| SCHEMBL554259 | 0.74 | ACHE (0.44) | TSHRALDH1A1MAPTHSD17B10CES2 | |
| SCHEMBL13879267 | 0.73 | TGFBR1 (0.44) | TSHRPLA2G2CTGFBR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5369204-A | Low molecular weight acrylamidoglycolate crosslinker and process | CYTEC TECHNOLOGY CORP. (US) | 1994-11-29 | — | — | US | disclosed |
| US-4760168-A | Preparation of alkyl acrylamidoglycolates and their alkyl ethers | AMERICAN CYANAMID COMPANY (US) | 1988-07-26 | — | — | US | disclosed |